Dysfunction of Myosin Light‐Chain 4 (MYL4) Leads to Heritable Atrial Cardiomyopathy With Electrical, Contractile, and Structural Components: Evidence From Genetically‐Engineered Rats

BACKGROUND: There is increasing interest in the concept of atrial cardiomyopathy, but the underlying molecular and mechanistic determinants remain poorly defined. We identified a family with heritable atrial cardiomyopathy manifesting as progressive atrial‐selective electromechanical dysfunction, ta...

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Detalles Bibliográficos
Autores principales: Peng, Wenhui, Li, Miaoxin, Li, Hailing, Tang, Kai, Zhuang, Jianhui, Zhang, Jianguo, Xiao, Jingjing, Jiang, Hui, Li, Dali, Yu, Yongchun, Sham, Pak C., Nattel, Stanley, Xu, Yawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721782/
https://www.ncbi.nlm.nih.gov/pubmed/29080865
http://dx.doi.org/10.1161/JAHA.117.007030

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