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Dispatch of Firefighters and Police Officers in Out‐of‐Hospital Cardiac Arrest: A Nationwide Prospective Cohort Trial Using Propensity Score Analysis

BACKGROUND: Dispatch of basic life support–trained first responders equipped with automated external defibrillators in addition to advanced life support–trained emergency medical services personnel in out‐of‐hospital cardiac arrest (OHCA) has, in some minor cohort studies, been associated with impro...

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Autores principales: Hasselqvist‐Ax, Ingela, Nordberg, Per, Herlitz, Johan, Svensson, Leif, Jonsson, Martin, Lindqvist, Jonny, Ringh, Mattias, Claesson, Andreas, Björklund, Johan, Andersson, Jan‐Otto, Ericson, Caroline, Lindblad, Pär, Engerström, Lars, Rosenqvist, Mårten, Hollenberg, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721830/
https://www.ncbi.nlm.nih.gov/pubmed/28978527
http://dx.doi.org/10.1161/JAHA.117.005873
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author Hasselqvist‐Ax, Ingela
Nordberg, Per
Herlitz, Johan
Svensson, Leif
Jonsson, Martin
Lindqvist, Jonny
Ringh, Mattias
Claesson, Andreas
Björklund, Johan
Andersson, Jan‐Otto
Ericson, Caroline
Lindblad, Pär
Engerström, Lars
Rosenqvist, Mårten
Hollenberg, Jacob
author_facet Hasselqvist‐Ax, Ingela
Nordberg, Per
Herlitz, Johan
Svensson, Leif
Jonsson, Martin
Lindqvist, Jonny
Ringh, Mattias
Claesson, Andreas
Björklund, Johan
Andersson, Jan‐Otto
Ericson, Caroline
Lindblad, Pär
Engerström, Lars
Rosenqvist, Mårten
Hollenberg, Jacob
author_sort Hasselqvist‐Ax, Ingela
collection PubMed
description BACKGROUND: Dispatch of basic life support–trained first responders equipped with automated external defibrillators in addition to advanced life support–trained emergency medical services personnel in out‐of‐hospital cardiac arrest (OHCA) has, in some minor cohort studies, been associated with improved survival. The aim of this study was to evaluate the association between basic life support plus advanced life support response and survival in OHCA at a national level. METHODS AND RESULTS: This prospective cohort study was conducted from January 1, 2012, to December 31, 2014. People who experienced OHCA in 9 Swedish counties covered by basic life support plus advanced life support response were compared with a propensity‐matched contemporary control group of people who experienced OHCA in 12 counties where only emergency medical services was dispatched, providing advanced life support. Primary outcome was survival to 30 days. The analytic sample consisted of 2786 pairs (n=5572) derived from the total cohort of 7308 complete cases. The median time from emergency call to arrival of emergency medical services or first responder was 9 minutes in the intervention group versus 10 minutes in the controls (P<0.001). The proportion of patients admitted alive to the hospital after resuscitation was 31.4% (875/2786) in the intervention group versus 24.9% (694/2786) in the controls (conditional odds ratio, 1.40; 95% confidence interval, 1.24–1.57). Thirty‐day survival was 9.5% (266/2786) in the intervention group versus 7.7% (214/2786) in the controls (conditional odds ratio, 1.27; 95% confidence interval, 1.05–1.54). CONCLUSIONS: In this nationwide interventional trial, using propensity score matching, dispatch of first responders in addition to emergency medical services in OHCA was associated with a moderate, but significant, increase in 30‐day survival. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT02184468.
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spelling pubmed-57218302017-12-12 Dispatch of Firefighters and Police Officers in Out‐of‐Hospital Cardiac Arrest: A Nationwide Prospective Cohort Trial Using Propensity Score Analysis Hasselqvist‐Ax, Ingela Nordberg, Per Herlitz, Johan Svensson, Leif Jonsson, Martin Lindqvist, Jonny Ringh, Mattias Claesson, Andreas Björklund, Johan Andersson, Jan‐Otto Ericson, Caroline Lindblad, Pär Engerström, Lars Rosenqvist, Mårten Hollenberg, Jacob J Am Heart Assoc Original Research BACKGROUND: Dispatch of basic life support–trained first responders equipped with automated external defibrillators in addition to advanced life support–trained emergency medical services personnel in out‐of‐hospital cardiac arrest (OHCA) has, in some minor cohort studies, been associated with improved survival. The aim of this study was to evaluate the association between basic life support plus advanced life support response and survival in OHCA at a national level. METHODS AND RESULTS: This prospective cohort study was conducted from January 1, 2012, to December 31, 2014. People who experienced OHCA in 9 Swedish counties covered by basic life support plus advanced life support response were compared with a propensity‐matched contemporary control group of people who experienced OHCA in 12 counties where only emergency medical services was dispatched, providing advanced life support. Primary outcome was survival to 30 days. The analytic sample consisted of 2786 pairs (n=5572) derived from the total cohort of 7308 complete cases. The median time from emergency call to arrival of emergency medical services or first responder was 9 minutes in the intervention group versus 10 minutes in the controls (P<0.001). The proportion of patients admitted alive to the hospital after resuscitation was 31.4% (875/2786) in the intervention group versus 24.9% (694/2786) in the controls (conditional odds ratio, 1.40; 95% confidence interval, 1.24–1.57). Thirty‐day survival was 9.5% (266/2786) in the intervention group versus 7.7% (214/2786) in the controls (conditional odds ratio, 1.27; 95% confidence interval, 1.05–1.54). CONCLUSIONS: In this nationwide interventional trial, using propensity score matching, dispatch of first responders in addition to emergency medical services in OHCA was associated with a moderate, but significant, increase in 30‐day survival. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT02184468. John Wiley and Sons Inc. 2017-10-04 /pmc/articles/PMC5721830/ /pubmed/28978527 http://dx.doi.org/10.1161/JAHA.117.005873 Text en © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Hasselqvist‐Ax, Ingela
Nordberg, Per
Herlitz, Johan
Svensson, Leif
Jonsson, Martin
Lindqvist, Jonny
Ringh, Mattias
Claesson, Andreas
Björklund, Johan
Andersson, Jan‐Otto
Ericson, Caroline
Lindblad, Pär
Engerström, Lars
Rosenqvist, Mårten
Hollenberg, Jacob
Dispatch of Firefighters and Police Officers in Out‐of‐Hospital Cardiac Arrest: A Nationwide Prospective Cohort Trial Using Propensity Score Analysis
title Dispatch of Firefighters and Police Officers in Out‐of‐Hospital Cardiac Arrest: A Nationwide Prospective Cohort Trial Using Propensity Score Analysis
title_full Dispatch of Firefighters and Police Officers in Out‐of‐Hospital Cardiac Arrest: A Nationwide Prospective Cohort Trial Using Propensity Score Analysis
title_fullStr Dispatch of Firefighters and Police Officers in Out‐of‐Hospital Cardiac Arrest: A Nationwide Prospective Cohort Trial Using Propensity Score Analysis
title_full_unstemmed Dispatch of Firefighters and Police Officers in Out‐of‐Hospital Cardiac Arrest: A Nationwide Prospective Cohort Trial Using Propensity Score Analysis
title_short Dispatch of Firefighters and Police Officers in Out‐of‐Hospital Cardiac Arrest: A Nationwide Prospective Cohort Trial Using Propensity Score Analysis
title_sort dispatch of firefighters and police officers in out‐of‐hospital cardiac arrest: a nationwide prospective cohort trial using propensity score analysis
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721830/
https://www.ncbi.nlm.nih.gov/pubmed/28978527
http://dx.doi.org/10.1161/JAHA.117.005873
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