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Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy

BACKGROUND: The optimal surgical approach for management of acute type A aortic dissection remains controversial. This study aimed to assess outcomes of reoperation after acute type A dissection repair to help guide decision making around index operative strategy. METHODS AND RESULTS: All aortic reo...

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Autores principales: Wang, Hanghang, Wagner, Matthew, Benrashid, Ehsan, Keenan, Jeffrey, Wang, Alice, Ranney, David, Yerokun, Babatunde, Gaca, Jeffrey G., McCann, Richard L., Hughes, G. Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721847/
https://www.ncbi.nlm.nih.gov/pubmed/28974497
http://dx.doi.org/10.1161/JAHA.117.006376
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author Wang, Hanghang
Wagner, Matthew
Benrashid, Ehsan
Keenan, Jeffrey
Wang, Alice
Ranney, David
Yerokun, Babatunde
Gaca, Jeffrey G.
McCann, Richard L.
Hughes, G. Chad
author_facet Wang, Hanghang
Wagner, Matthew
Benrashid, Ehsan
Keenan, Jeffrey
Wang, Alice
Ranney, David
Yerokun, Babatunde
Gaca, Jeffrey G.
McCann, Richard L.
Hughes, G. Chad
author_sort Wang, Hanghang
collection PubMed
description BACKGROUND: The optimal surgical approach for management of acute type A aortic dissection remains controversial. This study aimed to assess outcomes of reoperation after acute type A dissection repair to help guide decision making around index operative strategy. METHODS AND RESULTS: All aortic reoperations (n=129) at a single referral institution from August 2005 to April 2016 after prior acute type A dissection repair were reviewed. The primary outcome was 30‐day or in‐hospital mortality. Secondary outcomes included organ‐specific morbidity and 1‐ and 5‐year outcomes as estimated using the Kaplan–Meier method. The majority of initial reoperations were proximal aortic (aortic valve, aortic root, or ascending) or aortic arch procedures (62.5%, n=55); most initial reoperations were performed in the elective setting (83.1%, n=74). Additional nonstaged second or more reoperations were required in 21 patients (23.6%) after the initial reoperation, during a median follow‐up of 2.5 years after the initial reoperation. Thirty‐day or in‐hospital mortality for all reoperations was 7.0% (elective: 6.3%; nonelective: 11.1%) with acceptable rates of organ‐specific morbidity, given the procedural complexity. One‐ and 5‐year overall survival after initial reoperation was 85.9% and 64.9%, respectively, with aorta‐specific survival of 88% at 5 years. CONCLUSIONS: Reoperation after acute type A aortic dissection repair is associated with low rates of mortality and morbidity. These data support more limited index repair for acute type A dissection, especially for patients undergoing index repair in lower volume centers without expertise in extensive repair, because reoperations, if needed, can be performed safely in referral aortic centers.
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spelling pubmed-57218472017-12-12 Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy Wang, Hanghang Wagner, Matthew Benrashid, Ehsan Keenan, Jeffrey Wang, Alice Ranney, David Yerokun, Babatunde Gaca, Jeffrey G. McCann, Richard L. Hughes, G. Chad J Am Heart Assoc Original Research BACKGROUND: The optimal surgical approach for management of acute type A aortic dissection remains controversial. This study aimed to assess outcomes of reoperation after acute type A dissection repair to help guide decision making around index operative strategy. METHODS AND RESULTS: All aortic reoperations (n=129) at a single referral institution from August 2005 to April 2016 after prior acute type A dissection repair were reviewed. The primary outcome was 30‐day or in‐hospital mortality. Secondary outcomes included organ‐specific morbidity and 1‐ and 5‐year outcomes as estimated using the Kaplan–Meier method. The majority of initial reoperations were proximal aortic (aortic valve, aortic root, or ascending) or aortic arch procedures (62.5%, n=55); most initial reoperations were performed in the elective setting (83.1%, n=74). Additional nonstaged second or more reoperations were required in 21 patients (23.6%) after the initial reoperation, during a median follow‐up of 2.5 years after the initial reoperation. Thirty‐day or in‐hospital mortality for all reoperations was 7.0% (elective: 6.3%; nonelective: 11.1%) with acceptable rates of organ‐specific morbidity, given the procedural complexity. One‐ and 5‐year overall survival after initial reoperation was 85.9% and 64.9%, respectively, with aorta‐specific survival of 88% at 5 years. CONCLUSIONS: Reoperation after acute type A aortic dissection repair is associated with low rates of mortality and morbidity. These data support more limited index repair for acute type A dissection, especially for patients undergoing index repair in lower volume centers without expertise in extensive repair, because reoperations, if needed, can be performed safely in referral aortic centers. John Wiley and Sons Inc. 2017-10-03 /pmc/articles/PMC5721847/ /pubmed/28974497 http://dx.doi.org/10.1161/JAHA.117.006376 Text en © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Research
Wang, Hanghang
Wagner, Matthew
Benrashid, Ehsan
Keenan, Jeffrey
Wang, Alice
Ranney, David
Yerokun, Babatunde
Gaca, Jeffrey G.
McCann, Richard L.
Hughes, G. Chad
Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy
title Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy
title_full Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy
title_fullStr Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy
title_full_unstemmed Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy
title_short Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy
title_sort outcomes of reoperation after acute type a aortic dissection: implications for index repair strategy
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721847/
https://www.ncbi.nlm.nih.gov/pubmed/28974497
http://dx.doi.org/10.1161/JAHA.117.006376
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