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Angiotensin II Receptor–Neprilysin Inhibitor Sacubitril/Valsartan Improves Endothelial Dysfunction in Spontaneously Hypertensive Rats

BACKGROUND: We have previously demonstrated that antihypertensive treatment with renin‐angiotensin system inhibitors restores the impaired endothelium‐dependent hyperpolarization (EDH)–mediated responses in spontaneously hypertensive rats (SHRs). Herein, we investigated whether the angiotensin II re...

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Detalles Bibliográficos
Autores principales: Seki, Takunori, Goto, Kenichi, Kansui, Yasuo, Ohtsubo, Toshio, Matsumura, Kiyoshi, Kitazono, Takanari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721864/
https://www.ncbi.nlm.nih.gov/pubmed/29042424
http://dx.doi.org/10.1161/JAHA.117.006617