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Impact of Preoperative Anemia on Outcomes in Adults Undergoing Elective Posterior Cervical Fusion
STUDY DESIGN: Retrospective analysis of prospectively collected data. OBJECTIVES: Few studies have investigated the role of preoperative anemia on postoperative outcomes of posterior cervical fusion. This study looked to investigate the potential relationship between preoperative anemia and postoper...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722000/ https://www.ncbi.nlm.nih.gov/pubmed/29238644 http://dx.doi.org/10.1177/2192568217705654 |
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author | Phan, Kevin Dunn, Alexander E. Kim, Jun S. Capua, John Di Somani, Sulaiman Kothari, Parth Lee, Nathan J. Xu, Joshua Dowdell, James E. Cho, Samuel K. |
author_facet | Phan, Kevin Dunn, Alexander E. Kim, Jun S. Capua, John Di Somani, Sulaiman Kothari, Parth Lee, Nathan J. Xu, Joshua Dowdell, James E. Cho, Samuel K. |
author_sort | Phan, Kevin |
collection | PubMed |
description | STUDY DESIGN: Retrospective analysis of prospectively collected data. OBJECTIVES: Few studies have investigated the role of preoperative anemia on postoperative outcomes of posterior cervical fusion. This study looked to investigate the potential relationship between preoperative anemia and postoperative outcomes following posterior cervical spine fusion. METHODS: Data from patients undergoing elective posterior cervical fusions between 2005 and 2012 was collected from the American College of Surgeons National Surgical Quality Improvement Program database using inclusion/exclusion criteria. Multivariate analyses were used to identify the predictive power of anemia for postoperative outcomes. RESULTS: A total of 473 adult patients undergoing elective posterior cervical fusions were identified with 106 (22.4%) diagnosed with anemia preoperatively. Anemic patients had higher rates of diabetes (P = .0001), American Society of Anesthesiologists scores ≥3 (P < .0001), and higher dependent functional status prior to surgery (P < .0001). Intraoperatively, anemic patients also had higher rates of neuromuscular injuries (P = .0303), stroke (P = .013), bleeding disorders (P = .0056), lower albumin (P < .0001), lower hematocrit (P < .0001), and higher international normalized ratio (P = .002). Postoperatively, anemic patients had higher rates of complications (P < .0001), death (P = .008), blood transfusion (P = .001), reoperation (P = .012), unplanned readmission (P = .022), and extended length of stay (>5 days; P < .0001). CONCLUSIONS: Preoperative anemia is linked to a number of postoperative complications, which can increase length of hospital stay and increase the likelihood of reoperation. Identifying preoperative anemia may play a role in optimizing and minimizing the complication rates and severity of comorbidities following posterior cervical fusion. |
format | Online Article Text |
id | pubmed-5722000 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-57220002017-12-13 Impact of Preoperative Anemia on Outcomes in Adults Undergoing Elective Posterior Cervical Fusion Phan, Kevin Dunn, Alexander E. Kim, Jun S. Capua, John Di Somani, Sulaiman Kothari, Parth Lee, Nathan J. Xu, Joshua Dowdell, James E. Cho, Samuel K. Global Spine J Original Articles STUDY DESIGN: Retrospective analysis of prospectively collected data. OBJECTIVES: Few studies have investigated the role of preoperative anemia on postoperative outcomes of posterior cervical fusion. This study looked to investigate the potential relationship between preoperative anemia and postoperative outcomes following posterior cervical spine fusion. METHODS: Data from patients undergoing elective posterior cervical fusions between 2005 and 2012 was collected from the American College of Surgeons National Surgical Quality Improvement Program database using inclusion/exclusion criteria. Multivariate analyses were used to identify the predictive power of anemia for postoperative outcomes. RESULTS: A total of 473 adult patients undergoing elective posterior cervical fusions were identified with 106 (22.4%) diagnosed with anemia preoperatively. Anemic patients had higher rates of diabetes (P = .0001), American Society of Anesthesiologists scores ≥3 (P < .0001), and higher dependent functional status prior to surgery (P < .0001). Intraoperatively, anemic patients also had higher rates of neuromuscular injuries (P = .0303), stroke (P = .013), bleeding disorders (P = .0056), lower albumin (P < .0001), lower hematocrit (P < .0001), and higher international normalized ratio (P = .002). Postoperatively, anemic patients had higher rates of complications (P < .0001), death (P = .008), blood transfusion (P = .001), reoperation (P = .012), unplanned readmission (P = .022), and extended length of stay (>5 days; P < .0001). CONCLUSIONS: Preoperative anemia is linked to a number of postoperative complications, which can increase length of hospital stay and increase the likelihood of reoperation. Identifying preoperative anemia may play a role in optimizing and minimizing the complication rates and severity of comorbidities following posterior cervical fusion. SAGE Publications 2017-06-30 2017-12 /pmc/articles/PMC5722000/ /pubmed/29238644 http://dx.doi.org/10.1177/2192568217705654 Text en © The Author(s) 2017 http://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (http://www.creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Articles Phan, Kevin Dunn, Alexander E. Kim, Jun S. Capua, John Di Somani, Sulaiman Kothari, Parth Lee, Nathan J. Xu, Joshua Dowdell, James E. Cho, Samuel K. Impact of Preoperative Anemia on Outcomes in Adults Undergoing Elective Posterior Cervical Fusion |
title | Impact of Preoperative Anemia on Outcomes in Adults Undergoing Elective Posterior Cervical Fusion |
title_full | Impact of Preoperative Anemia on Outcomes in Adults Undergoing Elective Posterior Cervical Fusion |
title_fullStr | Impact of Preoperative Anemia on Outcomes in Adults Undergoing Elective Posterior Cervical Fusion |
title_full_unstemmed | Impact of Preoperative Anemia on Outcomes in Adults Undergoing Elective Posterior Cervical Fusion |
title_short | Impact of Preoperative Anemia on Outcomes in Adults Undergoing Elective Posterior Cervical Fusion |
title_sort | impact of preoperative anemia on outcomes in adults undergoing elective posterior cervical fusion |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722000/ https://www.ncbi.nlm.nih.gov/pubmed/29238644 http://dx.doi.org/10.1177/2192568217705654 |
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