Cargando…

Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique

Detalles Bibliográficos
Autores principales:	Hartwig, Fernando Pires, Davies, Neil Martin, Hemani, Gibran, Davey Smith, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Editorials
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722032/ https://www.ncbi.nlm.nih.gov/pubmed/28338968 http://dx.doi.org/10.1093/ije/dyx028

Ejemplares similares

Mendelian randomization: genetic anchors for causal inference in epidemiological studies
por: Davey Smith, George, et al.
Publicado: (2014)

Bias in Mendelian randomization due to assortative mating
por: Hartwig, Fernando Pires, et al.
Publicado: (2018)

Evaluating the potential role of pleiotropy in Mendelian randomization studies
por: Hemani, Gibran, et al.
Publicado: (2018)

Lung function, COPD and cognitive function: a multivariable and two sample Mendelian randomization study
por: Higbee, Daniel H., et al.
Publicado: (2021)

Evaluating and implementing block jackknife resampling Mendelian randomization to mitigate bias induced by overlapping samples
por: Fang, Si, et al.
Publicado: (2022)

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome
por: Richardson, Tom G., et al.
Publicado: (2020)

Invited Commentary: Detecting Individual and Global Horizontal Pleiotropy in Mendelian Randomization—A Job for the Humble Heterogeneity Statistic?
por: Bowden, Jack, et al.
Publicado: (2018)

The Fallibility of Scientific Evidence in Medical Jurisprudence
por: Hopkins, T. S.
Publicado: (1901)

The use of negative control outcomes in Mendelian randomization to detect potential population stratification
por: Sanderson, Eleanor, et al.
Publicado: (2021)

The downside to lymphocytes
por: Van Epps, Heather L.
Publicado: (2006)

The Downside of Globalization
por: Ziegler, Marc
Publicado: (2020)

On the fallibility of simulation models in informing pandemic responses
por: Gurdasani, Deepti, et al.
Publicado: (2020)

Inflammatory Biomarkers and Risk of Schizophrenia: A 2-Sample Mendelian Randomization Study
por: Hartwig, Fernando Pires, et al.
Publicado: (2017)

Bias in two-sample Mendelian randomization when using heritable covariable-adjusted summary associations
por: Hartwig, Fernando Pires, et al.
Publicado: (2021)

The downside of microtubule stability
por: Leslie, Mitch
Publicado: (2009)

The Downsides of Cognitive Enhancement
por: Colzato, Lorenza S., et al.
Publicado: (2020)

Assortative mating and within-spouse pair comparisons
por: Howe, Laurence J., et al.
Publicado: (2021)

Recent Developments in Mendelian Randomization Studies
por: Zheng, Jie, et al.
Publicado: (2017)

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses
por: Brumpton, Ben, et al.
Publicado: (2020)

Education, intelligence and Alzheimer’s disease: evidence from a multivariable two-sample Mendelian randomization study
por: Anderson, Emma L, et al.
Publicado: (2020)

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption
por: Hartwig, Fernando Pires, et al.
Publicado: (2017)

Schizophrenia risk and reproductive success: a Mendelian randomization study
por: Lawn, Rebecca B., et al.
Publicado: (2019)

On the fallibility of simulation models in informing pandemic responses – Authors' reply
por: Hellewell, Joel, et al.
Publicado: (2020)

Framing the fallibility of Computer-Aided Detection aids cancer detection
por: Kunar, Melina A., et al.
Publicado: (2023)

The Downside to Full Board Independence
por: Faleye, Olubunmi
Publicado: (2016)

The downside of mutual bond funds
por: Appel, Marvin, et al.
Publicado: (2011)

Population phenomena inflate genetic associations of complex social traits
por: Morris, Tim T., et al.
Publicado: (2020)

The fallibility of memory in judicial processes: Lessons from the past and their modern consequences
por: Howe, Mark L., et al.
Publicado: (2015)

Interaction-based Mendelian randomization with measured and unmeasured gene-by-covariate interactions
por: Spiller, Wes, et al.
Publicado: (2022)

Investigating the transparency of reporting in two-sample summary data Mendelian randomization studies using the MR-Base platform
por: Woolf, Benjamin, et al.
Publicado: (2022)

The Downside of Right Ventricular Apical Pacing
por: Brenyo, Andrew, et al.
Publicado: (2012)

Jocks versus Geeks—the Downside of Genius?
por: Roberts, Roland G.
Publicado: (2014)

Endogenous opioids: The downside of opposing stress
por: Valentino, Rita J., et al.
Publicado: (2014)

The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: a two-step, two-sample Mendelian randomisation study
por: Xu, Lin, et al.
Publicado: (2017)

Mendelian randomization in health research: Using appropriate genetic variants and avoiding biased estimates()
por: Taylor, Amy E., et al.
Publicado: (2014)

The rubber hand illusion is a fallible method to study ownership of prosthetic limbs
por: Zbinden, Jan, et al.
Publicado: (2021)

Exploiting horizontal pleiotropy to search for causal pathways within a Mendelian randomization framework
por: Cho, Yoonsu, et al.
Publicado: (2020)

The role of common genetic variation in educational attainment and income: evidence from the National Child Development Study
por: Davies, Neil M., et al.
Publicado: (2015)

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk
por: Richardson, Tom G., et al.
Publicado: (2017)

Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases
por: Zhao, Huiling, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m30fu1vo5aim3ge50p0aigcqm3