Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura

PURPOSE: To report the case of a 52-year-old man with Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura (ITP). OBSERVATIONS: Treatment with corticosteroids led to the resolution of hematologic findings within 1 week, and normal visual acuity was achieved...

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Autores principales: Awh, Caroline C., Modjtahedi, Bobeck S., Eliott, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722137/
https://www.ncbi.nlm.nih.gov/pubmed/29260065
http://dx.doi.org/10.1016/j.ajoc.2017.03.001
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author Awh, Caroline C.
Modjtahedi, Bobeck S.
Eliott, Dean
author_facet Awh, Caroline C.
Modjtahedi, Bobeck S.
Eliott, Dean
author_sort Awh, Caroline C.
collection PubMed
description PURPOSE: To report the case of a 52-year-old man with Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura (ITP). OBSERVATIONS: Treatment with corticosteroids led to the resolution of hematologic findings within 1 week, and normal visual acuity was achieved after 2 months with no additional treatment. CONCLUSIONS AND IMPORTANCE: This is the first reported association between Purtscher's retinopathy and ITP. Complement activation has been implicated in the pathogenesis of both ITP and Purtscher's retinopathy, and we suggest that the patient's systemic process accounted for the retinal findings.
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spelling pubmed-57221372017-12-19 Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura Awh, Caroline C. Modjtahedi, Bobeck S. Eliott, Dean Am J Ophthalmol Case Rep Case report PURPOSE: To report the case of a 52-year-old man with Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura (ITP). OBSERVATIONS: Treatment with corticosteroids led to the resolution of hematologic findings within 1 week, and normal visual acuity was achieved after 2 months with no additional treatment. CONCLUSIONS AND IMPORTANCE: This is the first reported association between Purtscher's retinopathy and ITP. Complement activation has been implicated in the pathogenesis of both ITP and Purtscher's retinopathy, and we suggest that the patient's systemic process accounted for the retinal findings. Elsevier 2017-03-09 /pmc/articles/PMC5722137/ /pubmed/29260065 http://dx.doi.org/10.1016/j.ajoc.2017.03.001 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case report
Awh, Caroline C.
Modjtahedi, Bobeck S.
Eliott, Dean
Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura
title Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura
title_full Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura
title_fullStr Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura
title_full_unstemmed Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura
title_short Purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura
title_sort purtscher's retinopathy as the presenting manifestation of immune thrombocytopenic purpura
topic Case report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722137/
https://www.ncbi.nlm.nih.gov/pubmed/29260065
http://dx.doi.org/10.1016/j.ajoc.2017.03.001
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