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Retinal findings in membranoproliferative glomerulonephritis
PURPOSE: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. OBSERVATIONS: Three women and one man were followed for a period of 1.5–37 years. Four patients (...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722170/ https://www.ncbi.nlm.nih.gov/pubmed/29260086 http://dx.doi.org/10.1016/j.ajoc.2017.06.011 |
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author | Mansour, Ahmad M. Lima, Luiz H. Arevalo, J. Fernando Amaro, Miguel Hage Lozano, Virginia Ghannam, Alaa Bou Chan, Errol W. |
author_facet | Mansour, Ahmad M. Lima, Luiz H. Arevalo, J. Fernando Amaro, Miguel Hage Lozano, Virginia Ghannam, Alaa Bou Chan, Errol W. |
author_sort | Mansour, Ahmad M. |
collection | PubMed |
description | PURPOSE: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. OBSERVATIONS: Three women and one man were followed for a period of 1.5–37 years. Four patients (8 eyes) had drusen detected at first fundus exam at age 24, 29, 50 and 55. Three patients (6 eyes) had diffuse thickening of Bruch's membrane, and two patients (3 eyes) had detachment of the retinal pigment epithelium with serous retinal detachment. Drusen tended to widen over a period of 10-year follow-up in one case. CONCLUSIONS AND IMPORTANCE: Drusen remain the ocular stigmata for MPGN occuring at an early age. The retinal disease is progressive with gradual thickening of Bruch's membrane and occurrence of retinal pigment epithelium detachment. |
format | Online Article Text |
id | pubmed-5722170 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-57221702017-12-19 Retinal findings in membranoproliferative glomerulonephritis Mansour, Ahmad M. Lima, Luiz H. Arevalo, J. Fernando Amaro, Miguel Hage Lozano, Virginia Ghannam, Alaa Bou Chan, Errol W. Am J Ophthalmol Case Rep Case report PURPOSE: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. OBSERVATIONS: Three women and one man were followed for a period of 1.5–37 years. Four patients (8 eyes) had drusen detected at first fundus exam at age 24, 29, 50 and 55. Three patients (6 eyes) had diffuse thickening of Bruch's membrane, and two patients (3 eyes) had detachment of the retinal pigment epithelium with serous retinal detachment. Drusen tended to widen over a period of 10-year follow-up in one case. CONCLUSIONS AND IMPORTANCE: Drusen remain the ocular stigmata for MPGN occuring at an early age. The retinal disease is progressive with gradual thickening of Bruch's membrane and occurrence of retinal pigment epithelium detachment. Elsevier 2017-06-22 /pmc/articles/PMC5722170/ /pubmed/29260086 http://dx.doi.org/10.1016/j.ajoc.2017.06.011 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case report Mansour, Ahmad M. Lima, Luiz H. Arevalo, J. Fernando Amaro, Miguel Hage Lozano, Virginia Ghannam, Alaa Bou Chan, Errol W. Retinal findings in membranoproliferative glomerulonephritis |
title | Retinal findings in membranoproliferative glomerulonephritis |
title_full | Retinal findings in membranoproliferative glomerulonephritis |
title_fullStr | Retinal findings in membranoproliferative glomerulonephritis |
title_full_unstemmed | Retinal findings in membranoproliferative glomerulonephritis |
title_short | Retinal findings in membranoproliferative glomerulonephritis |
title_sort | retinal findings in membranoproliferative glomerulonephritis |
topic | Case report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722170/ https://www.ncbi.nlm.nih.gov/pubmed/29260086 http://dx.doi.org/10.1016/j.ajoc.2017.06.011 |
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