Human Primary Liver Cancer -derived Organoid Cultures for disease modelling and drug screening

Human liver cancer research currently lacks in vitro models that faithfully recapitulate the pathophysiology of the original tumour. We recently described a novel, near-physiological organoid culture system, where primary human healthy liver cells form long-term expanding organoids that retain liver...

Descripción completa

Detalles Bibliográficos
Autores principales: Broutier, Laura, Mastrogiovanni, Gianmarco, Verstegen, Monique M.A., Francies, Hayley E., Gavarró, Lena Morrill, Bradshaw, Charles R, Allen, George E, Arnes-Benito, Robert, Sidorova, Olga, Gaspersz, Marcia P., Georgakopoulos, Nikitas, Koo, Bon-Kyoung, Dietmann, Sabine, Davies, Susan E., Praseedom, Raaj K., Lieshout, Ruby, IJzermans, Jan N. M., Wigmore, Stephen J, Saeb-Parsy, Kourosh, Garnett, Mathew J., van der Laan, Luc J.W., Huch, Meritxell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722201/
https://www.ncbi.nlm.nih.gov/pubmed/29131160
http://dx.doi.org/10.1038/nm.4438

Ejemplares similares

Ejemplares similares