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Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil

A previous study by our group reported the isolation and characterisation of Leptospira borgpetersenii serogroup Ballum strain 4E. This strain is of particular interest because it is highly virulent in the hamster model. In this study, we performed whole-genome shotgun genome sequencing of the strai...

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Autores principales: Eslabão, Marcus Redü, Kremer, Frederico Schmitt, Ramos, Rommel Thiago Juca, da Silva, Artur Luiz da Costa, Azevedo, Vasco Ariston de Carvalho, Pinto, Luciano da Silva, da Silva, Éverton Fagonde, Dellagostin, Odir Antônio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722270/
https://www.ncbi.nlm.nih.gov/pubmed/29236926
http://dx.doi.org/10.1590/0074-02760170111
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author Eslabão, Marcus Redü
Kremer, Frederico Schmitt
Ramos, Rommel Thiago Juca
da Silva, Artur Luiz da Costa
Azevedo, Vasco Ariston de Carvalho
Pinto, Luciano da Silva
da Silva, Éverton Fagonde
Dellagostin, Odir Antônio
author_facet Eslabão, Marcus Redü
Kremer, Frederico Schmitt
Ramos, Rommel Thiago Juca
da Silva, Artur Luiz da Costa
Azevedo, Vasco Ariston de Carvalho
Pinto, Luciano da Silva
da Silva, Éverton Fagonde
Dellagostin, Odir Antônio
author_sort Eslabão, Marcus Redü
collection PubMed
description A previous study by our group reported the isolation and characterisation of Leptospira borgpetersenii serogroup Ballum strain 4E. This strain is of particular interest because it is highly virulent in the hamster model. In this study, we performed whole-genome shotgun genome sequencing of the strain using the SOLiD sequencing platform. By assembling and analysing the new genome, we were able to identify novel features that have been previously overlooked in genome annotations of other strains belonging to the same species.
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spelling pubmed-57222702018-02-01 Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil Eslabão, Marcus Redü Kremer, Frederico Schmitt Ramos, Rommel Thiago Juca da Silva, Artur Luiz da Costa Azevedo, Vasco Ariston de Carvalho Pinto, Luciano da Silva da Silva, Éverton Fagonde Dellagostin, Odir Antônio Mem Inst Oswaldo Cruz Genome Announcement and Highlights A previous study by our group reported the isolation and characterisation of Leptospira borgpetersenii serogroup Ballum strain 4E. This strain is of particular interest because it is highly virulent in the hamster model. In this study, we performed whole-genome shotgun genome sequencing of the strain using the SOLiD sequencing platform. By assembling and analysing the new genome, we were able to identify novel features that have been previously overlooked in genome annotations of other strains belonging to the same species. Instituto Oswaldo Cruz, Ministério da Saúde 2018-02 /pmc/articles/PMC5722270/ /pubmed/29236926 http://dx.doi.org/10.1590/0074-02760170111 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Genome Announcement and Highlights
Eslabão, Marcus Redü
Kremer, Frederico Schmitt
Ramos, Rommel Thiago Juca
da Silva, Artur Luiz da Costa
Azevedo, Vasco Ariston de Carvalho
Pinto, Luciano da Silva
da Silva, Éverton Fagonde
Dellagostin, Odir Antônio
Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil
title Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil
title_full Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil
title_fullStr Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil
title_full_unstemmed Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil
title_short Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil
title_sort genome of leptospira borgpetersenii strain 4e, a highly virulent isolate obtained from mus musculus in southern brazil
topic Genome Announcement and Highlights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722270/
https://www.ncbi.nlm.nih.gov/pubmed/29236926
http://dx.doi.org/10.1590/0074-02760170111
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