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Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil
A previous study by our group reported the isolation and characterisation of Leptospira borgpetersenii serogroup Ballum strain 4E. This strain is of particular interest because it is highly virulent in the hamster model. In this study, we performed whole-genome shotgun genome sequencing of the strai...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722270/ https://www.ncbi.nlm.nih.gov/pubmed/29236926 http://dx.doi.org/10.1590/0074-02760170111 |
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author | Eslabão, Marcus Redü Kremer, Frederico Schmitt Ramos, Rommel Thiago Juca da Silva, Artur Luiz da Costa Azevedo, Vasco Ariston de Carvalho Pinto, Luciano da Silva da Silva, Éverton Fagonde Dellagostin, Odir Antônio |
author_facet | Eslabão, Marcus Redü Kremer, Frederico Schmitt Ramos, Rommel Thiago Juca da Silva, Artur Luiz da Costa Azevedo, Vasco Ariston de Carvalho Pinto, Luciano da Silva da Silva, Éverton Fagonde Dellagostin, Odir Antônio |
author_sort | Eslabão, Marcus Redü |
collection | PubMed |
description | A previous study by our group reported the isolation and characterisation of Leptospira borgpetersenii serogroup Ballum strain 4E. This strain is of particular interest because it is highly virulent in the hamster model. In this study, we performed whole-genome shotgun genome sequencing of the strain using the SOLiD sequencing platform. By assembling and analysing the new genome, we were able to identify novel features that have been previously overlooked in genome annotations of other strains belonging to the same species. |
format | Online Article Text |
id | pubmed-5722270 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Instituto Oswaldo Cruz, Ministério da Saúde |
record_format | MEDLINE/PubMed |
spelling | pubmed-57222702018-02-01 Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil Eslabão, Marcus Redü Kremer, Frederico Schmitt Ramos, Rommel Thiago Juca da Silva, Artur Luiz da Costa Azevedo, Vasco Ariston de Carvalho Pinto, Luciano da Silva da Silva, Éverton Fagonde Dellagostin, Odir Antônio Mem Inst Oswaldo Cruz Genome Announcement and Highlights A previous study by our group reported the isolation and characterisation of Leptospira borgpetersenii serogroup Ballum strain 4E. This strain is of particular interest because it is highly virulent in the hamster model. In this study, we performed whole-genome shotgun genome sequencing of the strain using the SOLiD sequencing platform. By assembling and analysing the new genome, we were able to identify novel features that have been previously overlooked in genome annotations of other strains belonging to the same species. Instituto Oswaldo Cruz, Ministério da Saúde 2018-02 /pmc/articles/PMC5722270/ /pubmed/29236926 http://dx.doi.org/10.1590/0074-02760170111 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Genome Announcement and Highlights Eslabão, Marcus Redü Kremer, Frederico Schmitt Ramos, Rommel Thiago Juca da Silva, Artur Luiz da Costa Azevedo, Vasco Ariston de Carvalho Pinto, Luciano da Silva da Silva, Éverton Fagonde Dellagostin, Odir Antônio Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil |
title | Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil |
title_full | Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil |
title_fullStr | Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil |
title_full_unstemmed | Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil |
title_short | Genome of Leptospira borgpetersenii strain 4E, a highly virulent isolate obtained from Mus musculus in southern Brazil |
title_sort | genome of leptospira borgpetersenii strain 4e, a highly virulent isolate obtained from mus musculus in southern brazil |
topic | Genome Announcement and Highlights |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722270/ https://www.ncbi.nlm.nih.gov/pubmed/29236926 http://dx.doi.org/10.1590/0074-02760170111 |
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