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Simple and rapid validated HPLC-fluorescence determination of perampanel in the plasma of patients with epilepsy

We present a simple and fast high-performance liquid chromatography method with fluorescence detection for the determination of the antiepileptic drug perampanel in human plasma. The chromatographic separation was performed on a Kinetex PFP (100 × 2.6 mm, 4.6 µm) column, using a mobile phase of sodi...

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Detalles Bibliográficos
Autores principales: Mohamed, Susan, Candela, Carmina, Riva, Roberto, Contin, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722279/
https://www.ncbi.nlm.nih.gov/pubmed/29234708
http://dx.doi.org/10.1016/j.plabm.2017.11.003