Hexokinase 2 (HK2), the tumor promoter in glioma, is downregulated by miR-218/Bmi1 pathway

In cancer, glycolysis driving enzymes and their regulating microRNAs are one of the key focus of oncology research lately. The glycolytic enzyme hexokinase 2 (HK2) is crucial for the Warburg effect in human glioma, the most common malignant brain tumor. In the present study, we studied the tumorigen...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Liu, Nan, Cheng, Yingduan, Jin, Weilin, Zhang, Pengxing, Wang, Xin, Yang, Hongwei, Xu, Xiaoshan, Wang, Zhen, Tu, Yanyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722312/
https://www.ncbi.nlm.nih.gov/pubmed/29220380
http://dx.doi.org/10.1371/journal.pone.0189353

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