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Synthesis of novel purpurealidin analogs and evaluation of their effect on the cancer-relevant potassium channel K(V)10.1
In the search for novel anticancer drugs, the potassium channel K(V)10.1 has emerged as an interesting cancer target. Here, we report a new group of K(V)10.1 inhibitors, namely the purpurealidin analogs. These alkaloids are produced by the Verongida sponges and are known for their wide variety of bi...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722316/ https://www.ncbi.nlm.nih.gov/pubmed/29220359 http://dx.doi.org/10.1371/journal.pone.0188811 |