PyMT-Maclow: A novel, inducible, murine model for determining the role of CD68 positive cells in breast tumor development

CD68(+) tumor-associated macrophages (TAMs) are pro-tumorigenic, pro-angiogenic and are associated with decreased survival rates in patients with cancer, including breast cancer. Non-specific models of macrophage ablation reduce the number of TAMs and limit the development of mammary tumors. However...

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Detalles Bibliográficos
Autores principales: Rumney, Robin M. H., Coffelt, Seth B., Neale, Terence A., Dhayade, Sandeep, Tozer, Gillian M., Miller, Gaynor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722323/
https://www.ncbi.nlm.nih.gov/pubmed/29220404
http://dx.doi.org/10.1371/journal.pone.0188591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722323/
https://www.ncbi.nlm.nih.gov/pubmed/29220404
http://dx.doi.org/10.1371/journal.pone.0188591

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