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PyMT-Maclow: A novel, inducible, murine model for determining the role of CD68 positive cells in breast tumor development
CD68(+) tumor-associated macrophages (TAMs) are pro-tumorigenic, pro-angiogenic and are associated with decreased survival rates in patients with cancer, including breast cancer. Non-specific models of macrophage ablation reduce the number of TAMs and limit the development of mammary tumors. However...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722323/ https://www.ncbi.nlm.nih.gov/pubmed/29220404 http://dx.doi.org/10.1371/journal.pone.0188591 |