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A technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials
This study aimed to validate and implement a methodology in which fiducials implanted in the periphery of lung tumors can be used to reduce uncertainties in tumor location. Alignment software that matches marker positions on two‐dimensional (2D) kilovoltage portal images to positions on three‐dimens...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722352/ https://www.ncbi.nlm.nih.gov/pubmed/19020478 http://dx.doi.org/10.1120/jacmp.v9i4.2766 |
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author | Nelson, Christopher Balter, Peter Morice, Rodolfo C. Choi, Bum Kudchadker, Rajat J. Bucci, Kara Chang, Joe Y. Dong, Lei Tucker, Susan Vedam, Sastry Briere, Tina Starkschall, George |
author_facet | Nelson, Christopher Balter, Peter Morice, Rodolfo C. Choi, Bum Kudchadker, Rajat J. Bucci, Kara Chang, Joe Y. Dong, Lei Tucker, Susan Vedam, Sastry Briere, Tina Starkschall, George |
author_sort | Nelson, Christopher |
collection | PubMed |
description | This study aimed to validate and implement a methodology in which fiducials implanted in the periphery of lung tumors can be used to reduce uncertainties in tumor location. Alignment software that matches marker positions on two‐dimensional (2D) kilovoltage portal images to positions on three‐dimensional (3D) computed tomography data sets was validated using static and moving phantoms. This software also was used to reduce uncertainties in tumor location in a patient with fiducials implanted in the periphery of a lung tumor. Alignment of fiducial locations in orthogonal projection images with corresponding fiducial locations in 3D data sets can position both static and moving phantoms with an accuracy of 1 mm. In a patient, alignment based on fiducial locations reduced systematic errors in the left–right direction by 3 mm and random errors by 2 mm, and random errors in the superior–inferior direction by 3 mm as measured by anterior–posterior cine images. Software that matches fiducial markers on 2D and 3D images is effective for aligning both static and moving fiducials before treatment and can be implemented to reduce patient setup uncertainties. PACS number: 81.40.Wx |
format | Online Article Text |
id | pubmed-5722352 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-57223522018-04-02 A technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials Nelson, Christopher Balter, Peter Morice, Rodolfo C. Choi, Bum Kudchadker, Rajat J. Bucci, Kara Chang, Joe Y. Dong, Lei Tucker, Susan Vedam, Sastry Briere, Tina Starkschall, George J Appl Clin Med Phys Radiation Oncology Physics This study aimed to validate and implement a methodology in which fiducials implanted in the periphery of lung tumors can be used to reduce uncertainties in tumor location. Alignment software that matches marker positions on two‐dimensional (2D) kilovoltage portal images to positions on three‐dimensional (3D) computed tomography data sets was validated using static and moving phantoms. This software also was used to reduce uncertainties in tumor location in a patient with fiducials implanted in the periphery of a lung tumor. Alignment of fiducial locations in orthogonal projection images with corresponding fiducial locations in 3D data sets can position both static and moving phantoms with an accuracy of 1 mm. In a patient, alignment based on fiducial locations reduced systematic errors in the left–right direction by 3 mm and random errors by 2 mm, and random errors in the superior–inferior direction by 3 mm as measured by anterior–posterior cine images. Software that matches fiducial markers on 2D and 3D images is effective for aligning both static and moving fiducials before treatment and can be implemented to reduce patient setup uncertainties. PACS number: 81.40.Wx John Wiley and Sons Inc. 2008-10-30 /pmc/articles/PMC5722352/ /pubmed/19020478 http://dx.doi.org/10.1120/jacmp.v9i4.2766 Text en © 2008 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Nelson, Christopher Balter, Peter Morice, Rodolfo C. Choi, Bum Kudchadker, Rajat J. Bucci, Kara Chang, Joe Y. Dong, Lei Tucker, Susan Vedam, Sastry Briere, Tina Starkschall, George A technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials |
title | A technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials |
title_full | A technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials |
title_fullStr | A technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials |
title_full_unstemmed | A technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials |
title_short | A technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials |
title_sort | technique for reducing patient setup uncertainties by aligning and verifying daily positioning of a moving tumor using implanted fiducials |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722352/ https://www.ncbi.nlm.nih.gov/pubmed/19020478 http://dx.doi.org/10.1120/jacmp.v9i4.2766 |
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