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A plesiotherapy technique for the post‐operative treatment of skin cancer using Ir192 microSelectron.
We describe a technique of postoperative irradiation of skin cancer using plesiotherapy with Ir192 high dose rate microSelectron afterloading system (Nucletron, Veenendaal, Netherlands). The clinically defined area is drawn on the skin and the flexible ‘skin applicator’ is then orientated so that th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722355/ https://www.ncbi.nlm.nih.gov/pubmed/19020493 http://dx.doi.org/10.1120/jacmp.v9i4.2890 |
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author | Abatzoglou, Ioannis Tsoutsou, Pelagia Koukourakis, Michael I. |
author_facet | Abatzoglou, Ioannis Tsoutsou, Pelagia Koukourakis, Michael I. |
author_sort | Abatzoglou, Ioannis |
collection | PubMed |
description | We describe a technique of postoperative irradiation of skin cancer using plesiotherapy with Ir192 high dose rate microSelectron afterloading system (Nucletron, Veenendaal, Netherlands). The clinically defined area is drawn on the skin and the flexible ‘skin applicator’ is then orientated so that the drawn skin area is encompassed within the catheter defined surface. Using a thin pewter wire, the skin drawn area is copied on the air‐adjacent surface of the applicator. Ex vivo CT simulation follows. The data are then transferred to the radiotherapy planning computer and the catheters are virtually reconstructed. The isodose curve chosen to prescribe the dose is 3 mm to 5 mm away from the skin surface. Three fractions of 8Gy are scheduled, 1 week apart, delivering a radiobiological equivalent of 48Gy of standard radiotherapy within 2 weeks. Our preliminary experience shows excellent early skin tolerance. The study is ongoing to assess efficacy and late effects. PACS number: 87.53.Jw |
format | Online Article Text |
id | pubmed-5722355 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-57223552018-04-02 A plesiotherapy technique for the post‐operative treatment of skin cancer using Ir192 microSelectron. Abatzoglou, Ioannis Tsoutsou, Pelagia Koukourakis, Michael I. J Appl Clin Med Phys Technical Notes We describe a technique of postoperative irradiation of skin cancer using plesiotherapy with Ir192 high dose rate microSelectron afterloading system (Nucletron, Veenendaal, Netherlands). The clinically defined area is drawn on the skin and the flexible ‘skin applicator’ is then orientated so that the drawn skin area is encompassed within the catheter defined surface. Using a thin pewter wire, the skin drawn area is copied on the air‐adjacent surface of the applicator. Ex vivo CT simulation follows. The data are then transferred to the radiotherapy planning computer and the catheters are virtually reconstructed. The isodose curve chosen to prescribe the dose is 3 mm to 5 mm away from the skin surface. Three fractions of 8Gy are scheduled, 1 week apart, delivering a radiobiological equivalent of 48Gy of standard radiotherapy within 2 weeks. Our preliminary experience shows excellent early skin tolerance. The study is ongoing to assess efficacy and late effects. PACS number: 87.53.Jw John Wiley and Sons Inc. 2008-10-29 /pmc/articles/PMC5722355/ /pubmed/19020493 http://dx.doi.org/10.1120/jacmp.v9i4.2890 Text en © 2008 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Technical Notes Abatzoglou, Ioannis Tsoutsou, Pelagia Koukourakis, Michael I. A plesiotherapy technique for the post‐operative treatment of skin cancer using Ir192 microSelectron. |
title | A plesiotherapy technique for the post‐operative treatment of skin cancer using Ir192 microSelectron. |
title_full | A plesiotherapy technique for the post‐operative treatment of skin cancer using Ir192 microSelectron. |
title_fullStr | A plesiotherapy technique for the post‐operative treatment of skin cancer using Ir192 microSelectron. |
title_full_unstemmed | A plesiotherapy technique for the post‐operative treatment of skin cancer using Ir192 microSelectron. |
title_short | A plesiotherapy technique for the post‐operative treatment of skin cancer using Ir192 microSelectron. |
title_sort | plesiotherapy technique for the post‐operative treatment of skin cancer using ir192 microselectron. |
topic | Technical Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722355/ https://www.ncbi.nlm.nih.gov/pubmed/19020493 http://dx.doi.org/10.1120/jacmp.v9i4.2890 |
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