A new homogeneity index based on statistical analysis of the dose–volume histogram

The goal of the present study was to develop a new dose–volume histogram (DVH)– based homogeneity index for effectively evaluating the dose homogeneity of intensity‐modulated radiotherapy plans. The new index, called the sigma‐index (“S‐index”) is defined as the standard deviation of the normalized...

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Detalles Bibliográficos
Autores principales: Yoon, Myonggeun, Park, Sung Yong, Shin, Dongho, Lee, Se Byeong, Pyo, Hong Ryull, Kim, Dae Yong, Cho, Kwan Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2007
Materias:
Radiation Oncology Physics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722417/
https://www.ncbi.nlm.nih.gov/pubmed/17592460
http://dx.doi.org/10.1120/jacmp.v8i2.2390
Descripción
Sumario:The goal of the present study was to develop a new dose–volume histogram (DVH)– based homogeneity index for effectively evaluating the dose homogeneity of intensity‐modulated radiotherapy plans. The new index, called the sigma‐index (“S‐index”) is defined as the standard deviation of the normalized differential DVH curve. In a study of 16 patients with brain tumors at our institution, the S‐index was found to vary from 0.80 to 3.15. Our results showed that the S‐index provides a more reliable and accurate measure of dose homogeneity than that given by conventional methods. A guideline for evaluating the dose homogeneity of treatment plans based on the S‐index and its relation to equivalent uniform dose is discussed. PACS numbers: 87.53.Xd, 87.53.Tf

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