A new homogeneity index based on statistical analysis of the dose–volume histogram

The goal of the present study was to develop a new dose–volume histogram (DVH)– based homogeneity index for effectively evaluating the dose homogeneity of intensity‐modulated radiotherapy plans. The new index, called the sigma‐index (“S‐index”) is defined as the standard deviation of the normalized...

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Autores principales: Yoon, Myonggeun, Park, Sung Yong, Shin, Dongho, Lee, Se Byeong, Pyo, Hong Ryull, Kim, Dae Yong, Cho, Kwan Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2007
Materias:
Radiation Oncology Physics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722417/
https://www.ncbi.nlm.nih.gov/pubmed/17592460
http://dx.doi.org/10.1120/jacmp.v8i2.2390
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author Yoon, Myonggeun
Park, Sung Yong
Shin, Dongho
Lee, Se Byeong
Pyo, Hong Ryull
Kim, Dae Yong
Cho, Kwan Ho
author_facet Yoon, Myonggeun
Park, Sung Yong
Shin, Dongho
Lee, Se Byeong
Pyo, Hong Ryull
Kim, Dae Yong
Cho, Kwan Ho
author_sort Yoon, Myonggeun
collection PubMed
description The goal of the present study was to develop a new dose–volume histogram (DVH)– based homogeneity index for effectively evaluating the dose homogeneity of intensity‐modulated radiotherapy plans. The new index, called the sigma‐index (“S‐index”) is defined as the standard deviation of the normalized differential DVH curve. In a study of 16 patients with brain tumors at our institution, the S‐index was found to vary from 0.80 to 3.15. Our results showed that the S‐index provides a more reliable and accurate measure of dose homogeneity than that given by conventional methods. A guideline for evaluating the dose homogeneity of treatment plans based on the S‐index and its relation to equivalent uniform dose is discussed. PACS numbers: 87.53.Xd, 87.53.Tf
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spelling pubmed-57224172018-04-02 A new homogeneity index based on statistical analysis of the dose–volume histogram Yoon, Myonggeun Park, Sung Yong Shin, Dongho Lee, Se Byeong Pyo, Hong Ryull Kim, Dae Yong Cho, Kwan Ho J Appl Clin Med Phys Radiation Oncology Physics The goal of the present study was to develop a new dose–volume histogram (DVH)– based homogeneity index for effectively evaluating the dose homogeneity of intensity‐modulated radiotherapy plans. The new index, called the sigma‐index (“S‐index”) is defined as the standard deviation of the normalized differential DVH curve. In a study of 16 patients with brain tumors at our institution, the S‐index was found to vary from 0.80 to 3.15. Our results showed that the S‐index provides a more reliable and accurate measure of dose homogeneity than that given by conventional methods. A guideline for evaluating the dose homogeneity of treatment plans based on the S‐index and its relation to equivalent uniform dose is discussed. PACS numbers: 87.53.Xd, 87.53.Tf John Wiley and Sons Inc. 2007-03-20 /pmc/articles/PMC5722417/ /pubmed/17592460 http://dx.doi.org/10.1120/jacmp.v8i2.2390 Text en © 2007 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Yoon, Myonggeun
Park, Sung Yong
Shin, Dongho
Lee, Se Byeong
Pyo, Hong Ryull
Kim, Dae Yong
Cho, Kwan Ho
A new homogeneity index based on statistical analysis of the dose–volume histogram
title A new homogeneity index based on statistical analysis of the dose–volume histogram
title_full A new homogeneity index based on statistical analysis of the dose–volume histogram
title_fullStr A new homogeneity index based on statistical analysis of the dose–volume histogram
title_full_unstemmed A new homogeneity index based on statistical analysis of the dose–volume histogram
title_short A new homogeneity index based on statistical analysis of the dose–volume histogram
title_sort new homogeneity index based on statistical analysis of the dose–volume histogram
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722417/
https://www.ncbi.nlm.nih.gov/pubmed/17592460
http://dx.doi.org/10.1120/jacmp.v8i2.2390
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