The dosimetric effect of inhomogeneity correction in dynamic conformal arc stereotactic body radiation therapy for lung tumors

For patients treated with lung stereotactic body radiation therapy (SBRT) using dynamic conformal arcs, the influence of inhomogeneity correction (IC) on normal tissue and tumor dosimetry was studied. For the same numbers of monitor units, the planning target volume equivalent uniform doses calculat...

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Autores principales: Kavanagh, Brian, Ding, Meisong, Schefter, Tracey, Stuhr, Kelly, Newman, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2006
Materias:
Radiation Oncology Physics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722435/
https://www.ncbi.nlm.nih.gov/pubmed/17533331
http://dx.doi.org/10.1120/jacmp.v7i2.2236
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author Kavanagh, Brian
Ding, Meisong
Schefter, Tracey
Stuhr, Kelly
Newman, Francis
author_facet Kavanagh, Brian
Ding, Meisong
Schefter, Tracey
Stuhr, Kelly
Newman, Francis
author_sort Kavanagh, Brian
collection PubMed
description For patients treated with lung stereotactic body radiation therapy (SBRT) using dynamic conformal arcs, the influence of inhomogeneity correction (IC) on normal tissue and tumor dosimetry was studied. For the same numbers of monitor units, the planning target volume equivalent uniform doses calculated without path‐length IC were lower than those calculated with IC (mean difference 18%, range 1% to 34%; [Formula: see text]). Normal lung dose differences were of the same magnitude in the opposite direction. In reports of SBRT, it will be helpful to maintain clear communication about the type of IC used to avoid future uncertainties about true normal tissue tolerance and tumor dose‐response relationships. PACS numbers: 87.50.Gi, 87.53.Bn, 87.53.Kn
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spelling pubmed-57224352018-04-02 The dosimetric effect of inhomogeneity correction in dynamic conformal arc stereotactic body radiation therapy for lung tumors Kavanagh, Brian Ding, Meisong Schefter, Tracey Stuhr, Kelly Newman, Francis J Appl Clin Med Phys Radiation Oncology Physics For patients treated with lung stereotactic body radiation therapy (SBRT) using dynamic conformal arcs, the influence of inhomogeneity correction (IC) on normal tissue and tumor dosimetry was studied. For the same numbers of monitor units, the planning target volume equivalent uniform doses calculated without path‐length IC were lower than those calculated with IC (mean difference 18%, range 1% to 34%; [Formula: see text]). Normal lung dose differences were of the same magnitude in the opposite direction. In reports of SBRT, it will be helpful to maintain clear communication about the type of IC used to avoid future uncertainties about true normal tissue tolerance and tumor dose‐response relationships. PACS numbers: 87.50.Gi, 87.53.Bn, 87.53.Kn John Wiley and Sons Inc. 2006-05-25 /pmc/articles/PMC5722435/ /pubmed/17533331 http://dx.doi.org/10.1120/jacmp.v7i2.2236 Text en © 2006 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Kavanagh, Brian
Ding, Meisong
Schefter, Tracey
Stuhr, Kelly
Newman, Francis
The dosimetric effect of inhomogeneity correction in dynamic conformal arc stereotactic body radiation therapy for lung tumors
title The dosimetric effect of inhomogeneity correction in dynamic conformal arc stereotactic body radiation therapy for lung tumors
title_full The dosimetric effect of inhomogeneity correction in dynamic conformal arc stereotactic body radiation therapy for lung tumors
title_fullStr The dosimetric effect of inhomogeneity correction in dynamic conformal arc stereotactic body radiation therapy for lung tumors
title_full_unstemmed The dosimetric effect of inhomogeneity correction in dynamic conformal arc stereotactic body radiation therapy for lung tumors
title_short The dosimetric effect of inhomogeneity correction in dynamic conformal arc stereotactic body radiation therapy for lung tumors
title_sort dosimetric effect of inhomogeneity correction in dynamic conformal arc stereotactic body radiation therapy for lung tumors
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722435/
https://www.ncbi.nlm.nih.gov/pubmed/17533331
http://dx.doi.org/10.1120/jacmp.v7i2.2236
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