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Applicator volume elimination methods and their influence on DVH analysis of HDR prostate implants

In CT anatomy‐based inverse treatment planning of interstitial high‐dose rate (HDR) brachytherapy planning, the planning target volume (PTV) delineated by the radiation oncologist includes the applicator volume. The applicator volume can be eliminated with the help of two methods: one based on Boole...

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Autores principales: Vivekanandan, Nagarajan, Kunjithapatham, Bhuvana, Kanakavelu, Nithya, Irde, Balakrishnan Shankarrao, Vaidyanathan, Lakshmanan Alathurmadam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722442/
https://www.ncbi.nlm.nih.gov/pubmed/17533328
http://dx.doi.org/10.1120/jacmp.v7i2.2213
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author Vivekanandan, Nagarajan
Kunjithapatham, Bhuvana
Kanakavelu, Nithya
Irde, Balakrishnan Shankarrao
Vaidyanathan, Lakshmanan Alathurmadam
author_facet Vivekanandan, Nagarajan
Kunjithapatham, Bhuvana
Kanakavelu, Nithya
Irde, Balakrishnan Shankarrao
Vaidyanathan, Lakshmanan Alathurmadam
author_sort Vivekanandan, Nagarajan
collection PubMed
description In CT anatomy‐based inverse treatment planning of interstitial high‐dose rate (HDR) brachytherapy planning, the planning target volume (PTV) delineated by the radiation oncologist includes the applicator volume. The applicator volume can be eliminated with the help of two methods: one based on Boolean operations and the other using the erasing option of the application software. Both methods are compared, and the results are discussed. Elimination of the applicator volume results in the proper estimation of the PTV and the exclusion of the clinically insignificant hot volume from the PTV in the dose‐volume histogram (DVH) analysis. Five cases of prostate cancer are considered for analysis. The PTV, applicator volume, maximum, mean, modal, and minimum dose, and the percentage volume of the PTV structure receiving the percent dose for both cases, that is, with and without applicator volume, are tabulated and analyzed. The elimination of the applicator volume results in the proper volume estimation of the PTV structure and leads to better DVH analysis of interstitial HDR prostate implants. The procedure would have little relevance in routine planning but improves dose reporting. It is too early to conclude its clinical significance or insignificance. PACS numbers: 57.53.Jw, 87.53.Tf
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spelling pubmed-57224422018-04-02 Applicator volume elimination methods and their influence on DVH analysis of HDR prostate implants Vivekanandan, Nagarajan Kunjithapatham, Bhuvana Kanakavelu, Nithya Irde, Balakrishnan Shankarrao Vaidyanathan, Lakshmanan Alathurmadam J Appl Clin Med Phys Radiation Oncology Physics In CT anatomy‐based inverse treatment planning of interstitial high‐dose rate (HDR) brachytherapy planning, the planning target volume (PTV) delineated by the radiation oncologist includes the applicator volume. The applicator volume can be eliminated with the help of two methods: one based on Boolean operations and the other using the erasing option of the application software. Both methods are compared, and the results are discussed. Elimination of the applicator volume results in the proper estimation of the PTV and the exclusion of the clinically insignificant hot volume from the PTV in the dose‐volume histogram (DVH) analysis. Five cases of prostate cancer are considered for analysis. The PTV, applicator volume, maximum, mean, modal, and minimum dose, and the percentage volume of the PTV structure receiving the percent dose for both cases, that is, with and without applicator volume, are tabulated and analyzed. The elimination of the applicator volume results in the proper volume estimation of the PTV structure and leads to better DVH analysis of interstitial HDR prostate implants. The procedure would have little relevance in routine planning but improves dose reporting. It is too early to conclude its clinical significance or insignificance. PACS numbers: 57.53.Jw, 87.53.Tf John Wiley and Sons Inc. 2006-05-25 /pmc/articles/PMC5722442/ /pubmed/17533328 http://dx.doi.org/10.1120/jacmp.v7i2.2213 Text en © 2006 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Vivekanandan, Nagarajan
Kunjithapatham, Bhuvana
Kanakavelu, Nithya
Irde, Balakrishnan Shankarrao
Vaidyanathan, Lakshmanan Alathurmadam
Applicator volume elimination methods and their influence on DVH analysis of HDR prostate implants
title Applicator volume elimination methods and their influence on DVH analysis of HDR prostate implants
title_full Applicator volume elimination methods and their influence on DVH analysis of HDR prostate implants
title_fullStr Applicator volume elimination methods and their influence on DVH analysis of HDR prostate implants
title_full_unstemmed Applicator volume elimination methods and their influence on DVH analysis of HDR prostate implants
title_short Applicator volume elimination methods and their influence on DVH analysis of HDR prostate implants
title_sort applicator volume elimination methods and their influence on dvh analysis of hdr prostate implants
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722442/
https://www.ncbi.nlm.nih.gov/pubmed/17533328
http://dx.doi.org/10.1120/jacmp.v7i2.2213
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