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Human cytomegalovirus and Herpes Simplex type I virus can engage RNA polymerase I for transcription of immediate early genes

Human cytomegalovirus (HCMV) utilizes RNA polymerase II to transcribe viral genes and produce viral mRNAs. It can specifically target the nucleolus to facilitate viral transcription and translation. As RNA polymerase I (Pol I)-mediated transcription is active in the nucleolus, we investigated the ro...

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Detalles Bibliográficos
Autores principales: Kostopoulou, Ourania N., Wilhelmi, Vanessa, Raiss, Sina, Ananthaseshan, Sharan, Lindström, Mikael S., Bartek, Jiri, Söderberg-Naucler, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722503/
https://www.ncbi.nlm.nih.gov/pubmed/29228551
http://dx.doi.org/10.18632/oncotarget.22106

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