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Human cytomegalovirus and Herpes Simplex type I virus can engage RNA polymerase I for transcription of immediate early genes
Human cytomegalovirus (HCMV) utilizes RNA polymerase II to transcribe viral genes and produce viral mRNAs. It can specifically target the nucleolus to facilitate viral transcription and translation. As RNA polymerase I (Pol I)-mediated transcription is active in the nucleolus, we investigated the ro...
Autores principales: | Kostopoulou, Ourania N., Wilhelmi, Vanessa, Raiss, Sina, Ananthaseshan, Sharan, Lindström, Mikael S., Bartek, Jiri, Söderberg-Naucler, Cecilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722503/ https://www.ncbi.nlm.nih.gov/pubmed/29228551 http://dx.doi.org/10.18632/oncotarget.22106 |
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