Interleukin-17A-promoted MSC2 polarization related with new bone formation of ankylosing spondylitis

It’s still unknown how over-hyperplasia of tissue such like new bone formation (NBF) developed in ankylosing spondylitis (AS). We found low level of IL-17A promoted TLR4+MSC1 polarization with suppressed osteogenic differentiation through JAK2/STAT3 pathway, while high level of IL-17A promoted TLR3+...

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Detalles Bibliográficos
Autores principales: He, Tao, Huang, Yan, Zhang, Chen, Liu, Denghui, Cheng, Chao, Xu, Weidong, Zhang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722540/
https://www.ncbi.nlm.nih.gov/pubmed/29228588
http://dx.doi.org/10.18632/oncotarget.20823

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