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Proteasome inhibitor bortezomib enhances the effect of standard chemotherapy in small cell lung cancer
Small cell lung cancer (SCLC) is an aggressive cancer showing a very poor prognosis because of metastasis formation at an early stage and acquisition of chemoresistance. One key driver of chemoresistance is the transcription factor Forkhead box protein M1 (FOXM1) that regulates cell cycle proliferat...
Autores principales: | Taromi, Sanaz, Lewens, Florentine, Arsenic, Ruza, Sedding, Dagmar, Sänger, Jörg, Kunze, Almut, Möbs, Markus, Benecke, Joana, Freitag, Helma, Christen, Friederike, Kaemmerer, Daniel, Lupp, Amelie, Heilmann, Mareike, Lammert, Hedwig, Schneider, Claus-Peter, Richter, Karen, Hummel, Michael, Siegmund, Britta, Burger, Meike, Briest, Franziska, Grabowski, Patricia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722545/ https://www.ncbi.nlm.nih.gov/pubmed/29228593 http://dx.doi.org/10.18632/oncotarget.21221 |
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