Identifying tumor promoting genomic alterations in tumor-associated fibroblasts via retrovirus-insertional mutagenesis

Tumor-associated fibroblasts (TAFs) are often essential for solid tumor growth. However, few genetic or epigenetic alterations have been found in TAFs during the progression of solid tumors. Employing a tumor-stromal cell co-injection model, we adapted here retroviral-insertional mutagenesis to stro...

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Detalles Bibliográficos
Autores principales: Rong, Lijie, Bian, Yangyang, Liu, Shubai, Liu, Xiaoman, Li, Xiao, Liu, Haiyang, Zhou, Jinxue, Peng, Jirun, Zhang, Henghui, Chen, Hongsong, Qin, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722558/
https://www.ncbi.nlm.nih.gov/pubmed/29228606
http://dx.doi.org/10.18632/oncotarget.21881

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