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BRCA mutations in the manifestation and treatment of ovarian cancer

BRCA genes are important for the integrity and stability of genetic material and play key roles in repairing DNA breaks via high fidelity homologous recombination. BRCA mutations are known to predispose carriers to gynecological malignancies, accounting for a majority of hereditary OC cases. Known t...

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Detalles Bibliográficos
Autores principales:	Pan, Zimin, Xie, Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722593/ https://www.ncbi.nlm.nih.gov/pubmed/29228641 http://dx.doi.org/10.18632/oncotarget.18280

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