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Effects of static dosimetric leaf gap on MLC‐based small‐beam dose distribution for intensity‐modulated radiosurgery

The aim of the present study was to evaluate the effect of various specific dosimetric leaf gaps on the multileaf collimator (MLC)–based small‐beam dose distribution. The dosimetric static leaf gap was determined by comparing the profiles of small MLC‐based beams with those of small collimated field...

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Autores principales: Lee, Jeong‐Woo, Choi, Kyoung‐Sik, Hong, Semie, Kim, Yon‐Lae, Chung, Jin‐Beom, Lee, Doo‐Hyun, Choe, Bo‐Young, Jang, Hong‐Seok, Suh, Tae‐Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722628/
https://www.ncbi.nlm.nih.gov/pubmed/18449146
http://dx.doi.org/10.1120/jacmp.v8i4.2397
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author Lee, Jeong‐Woo
Choi, Kyoung‐Sik
Hong, Semie
Kim, Yon‐Lae
Chung, Jin‐Beom
Lee, Doo‐Hyun
Choe, Bo‐Young
Jang, Hong‐Seok
Suh, Tae‐Suk
author_facet Lee, Jeong‐Woo
Choi, Kyoung‐Sik
Hong, Semie
Kim, Yon‐Lae
Chung, Jin‐Beom
Lee, Doo‐Hyun
Choe, Bo‐Young
Jang, Hong‐Seok
Suh, Tae‐Suk
author_sort Lee, Jeong‐Woo
collection PubMed
description The aim of the present study was to evaluate the effect of various specific dosimetric leaf gaps on the multileaf collimator (MLC)–based small‐beam dose distribution. The dosimetric static leaf gap was determined by comparing the profiles of small MLC‐based beams with those of small collimated fields (square fields of 1, 2, 3, and 4cm). The results showed that an approximately 2‐mm gap was optimal with the Millennium 120‐leaf MLC (Varian Medical Systems, Palo Alto, CA) and a Varian 21EX 6‐MV photon beam. We also investigated how much the leaf gap affects the planning results and the actual dose distribution. A doughnut‐shaped planning target volume (PTV, 6.1 cm(3)) and inner organ at risk (OAR, 0.3 cm(3)) were delineated for delicate intensity‐modulated radiosurgery test planning. The applied leaf gaps were 0, 1, and 2 mm. The measured dose distributions were compared with the dose distribution in the treatment planning system. The maximum dose differences at inside PTV, outside PTV, and inner OAR were, respectively, 22.3%, 20.2%, and 35.2% for the 0‐mm leaf gap; 17.8%, 22.8%, and 30.8% for the 1‐mm leaf gap; and 5.5%, 8.5%, and 6.3% for the 2‐mm leaf gap. In a human head phantom (model 605: CIRS, Norfolk, VA) study, large dose differences of 1.3% – 12.7% were noted for the measurements made using the MLC files generated by the three different leaf gaps. The planned results were similar, and measurements showed a large dose difference associated with the various leaf gaps. These results strongly suggest that plans generated by a commercial inverse planning system commissioned using general collimated field data will probably demonstrate discrepancies between the planned treatments and the measured results. PACS number: 87.53.Dq
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spelling pubmed-57226282018-04-02 Effects of static dosimetric leaf gap on MLC‐based small‐beam dose distribution for intensity‐modulated radiosurgery Lee, Jeong‐Woo Choi, Kyoung‐Sik Hong, Semie Kim, Yon‐Lae Chung, Jin‐Beom Lee, Doo‐Hyun Choe, Bo‐Young Jang, Hong‐Seok Suh, Tae‐Suk J Appl Clin Med Phys Radiation Oncology Physics The aim of the present study was to evaluate the effect of various specific dosimetric leaf gaps on the multileaf collimator (MLC)–based small‐beam dose distribution. The dosimetric static leaf gap was determined by comparing the profiles of small MLC‐based beams with those of small collimated fields (square fields of 1, 2, 3, and 4cm). The results showed that an approximately 2‐mm gap was optimal with the Millennium 120‐leaf MLC (Varian Medical Systems, Palo Alto, CA) and a Varian 21EX 6‐MV photon beam. We also investigated how much the leaf gap affects the planning results and the actual dose distribution. A doughnut‐shaped planning target volume (PTV, 6.1 cm(3)) and inner organ at risk (OAR, 0.3 cm(3)) were delineated for delicate intensity‐modulated radiosurgery test planning. The applied leaf gaps were 0, 1, and 2 mm. The measured dose distributions were compared with the dose distribution in the treatment planning system. The maximum dose differences at inside PTV, outside PTV, and inner OAR were, respectively, 22.3%, 20.2%, and 35.2% for the 0‐mm leaf gap; 17.8%, 22.8%, and 30.8% for the 1‐mm leaf gap; and 5.5%, 8.5%, and 6.3% for the 2‐mm leaf gap. In a human head phantom (model 605: CIRS, Norfolk, VA) study, large dose differences of 1.3% – 12.7% were noted for the measurements made using the MLC files generated by the three different leaf gaps. The planned results were similar, and measurements showed a large dose difference associated with the various leaf gaps. These results strongly suggest that plans generated by a commercial inverse planning system commissioned using general collimated field data will probably demonstrate discrepancies between the planned treatments and the measured results. PACS number: 87.53.Dq John Wiley and Sons Inc. 2007-10-24 /pmc/articles/PMC5722628/ /pubmed/18449146 http://dx.doi.org/10.1120/jacmp.v8i4.2397 Text en © 2007 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Lee, Jeong‐Woo
Choi, Kyoung‐Sik
Hong, Semie
Kim, Yon‐Lae
Chung, Jin‐Beom
Lee, Doo‐Hyun
Choe, Bo‐Young
Jang, Hong‐Seok
Suh, Tae‐Suk
Effects of static dosimetric leaf gap on MLC‐based small‐beam dose distribution for intensity‐modulated radiosurgery
title Effects of static dosimetric leaf gap on MLC‐based small‐beam dose distribution for intensity‐modulated radiosurgery
title_full Effects of static dosimetric leaf gap on MLC‐based small‐beam dose distribution for intensity‐modulated radiosurgery
title_fullStr Effects of static dosimetric leaf gap on MLC‐based small‐beam dose distribution for intensity‐modulated radiosurgery
title_full_unstemmed Effects of static dosimetric leaf gap on MLC‐based small‐beam dose distribution for intensity‐modulated radiosurgery
title_short Effects of static dosimetric leaf gap on MLC‐based small‐beam dose distribution for intensity‐modulated radiosurgery
title_sort effects of static dosimetric leaf gap on mlc‐based small‐beam dose distribution for intensity‐modulated radiosurgery
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722628/
https://www.ncbi.nlm.nih.gov/pubmed/18449146
http://dx.doi.org/10.1120/jacmp.v8i4.2397
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