Cargando…
Direct N-alkylation of unprotected amino acids with alcohols
N-alkyl amino acids find widespread application as highly valuable, renewable building blocks. However, traditional synthesis methodologies to obtain these suffer from serious limitations, providing a major challenge to develop sustainable alternatives. We report the first powerful catalytic strateg...
Autores principales: | Yan, Tao, Feringa, Ben L., Barta, Katalin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722651/ https://www.ncbi.nlm.nih.gov/pubmed/29226249 http://dx.doi.org/10.1126/sciadv.aao6494 |
Ejemplares similares
-
Direct Catalytic N‐Alkylation of α‐Amino Acid Esters and Amides Using Alcohols with High Retention of Stereochemistry
por: Yan, Tao, et al.
Publicado: (2021) -
Ruthenium and Iron‐Catalysed Decarboxylative N‐alkylation of Cyclic α‐Amino Acids with Alcohols: Sustainable Routes to Pyrrolidine and Piperidine Derivatives
por: Afanasenko, Anastasiia, et al.
Publicado: (2019) -
Catalytic asymmetric Tsuji–Trost α−benzylation reaction of N-unprotected amino acids and benzyl alcohol derivatives
por: Liu, Jian-Hua, et al.
Publicado: (2022) -
Chiral aldehyde catalysis enables direct asymmetric α-substitution reaction of N-unprotected amino acids with halohydrocarbons
por: Shen, Hao-Ran, et al.
Publicado: (2023) -
Enantioselective extraction of unprotected amino acids coupled with racemization
por: Huang, Haofei, et al.
Publicado: (2021)