Suitability of various chromatographic and spectroscopic techniques for analysis and kinetic degradation study of trelagliptin

Multifaceted comparative analytical methods for trelagliptin (TRL) were investigated, applied to ZAFATEK tablets and HPLC-UV was selected for a degradation kinetic study. UPLC-MS/MS (Method I), UPLC-UV (Method II), HPLC-UV (Method III), UHPLC-UV (Method IV) and direct UV (Method V) methods were deve...

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Detalles Bibliográficos
Autores principales: Zaghary, Wafaa A., Mowaka, Shereen, Hassan, Mostafa A., Ayoub, Bassam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722889/
https://www.ncbi.nlm.nih.gov/pubmed/29222475
http://dx.doi.org/10.1038/s41598-017-17642-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722889/
https://www.ncbi.nlm.nih.gov/pubmed/29222475
http://dx.doi.org/10.1038/s41598-017-17642-1

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