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Virtual screening for inhibitors of the human TSLP:TSLPR interaction

The pro-inflammatory cytokine thymic stromal lymphopoietin (TSLP) plays a pivotal role in the pathophysiology of various allergy disorders that are mediated by type 2 helper T cell (Th2) responses, such as asthma and atopic dermatitis. TSLP forms a ternary complex with the TSLP receptor (TSLPR) and...

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Detalles Bibliográficos
Autores principales:	Van Rompaey, Dries, Verstraete, Kenneth, Peelman, Frank, Savvides, Savvas N., Augustyns, Koen, Van Der Veken, Pieter, De Winter, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722893/ https://www.ncbi.nlm.nih.gov/pubmed/29222519 http://dx.doi.org/10.1038/s41598-017-17620-7

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