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Structural Dynamics of the MscL C-terminal Domain

The large conductance mechanosensitive channel (MscL), acts as an osmoprotective emergency valve in bacteria by opening a large, water-filled pore in response to changes in membrane tension. In its closed configuration, the last 36 residues at the C-terminus form a bundle of five α-helices co-linear...

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Detalles Bibliográficos
Autores principales: Bavi, Navid, Martinac, Adam D., Cortes, D. Marien, Bavi, Omid, Ridone, Pietro, Nomura, Takeshi, Hill, Adam P., Martinac, Boris, Perozo, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722894/
https://www.ncbi.nlm.nih.gov/pubmed/29222414
http://dx.doi.org/10.1038/s41598-017-17396-w

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