Cargando…

Stromal Versican Regulates Tumor Growth by Promoting Angiogenesis

The proteoglycan versican is implicated in growth and metastases of several cancers. Here we investigated a potential contribution of stromal versican to tumor growth and angiogenesis. We initially determined versican expression by several cancer cell lines. Among these, MDA-MB231 and B16F10 had non...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asano, Keiichi, Nelson, Courtney M., Nandadasa, Sumeda, Aramaki-Hattori, Noriko, Lindner, Daniel J., Alban, Tyler, Inagaki, Junko, Ohtsuki, Takashi, Oohashi, Toshitaka, Apte, Suneel S., Hirohata, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722896/ https://www.ncbi.nlm.nih.gov/pubmed/29222454 http://dx.doi.org/10.1038/s41598-017-17613-6

Ejemplares similares

A new mouse mutant with cleavage-resistant versican and isoform-specific versican mutants demonstrate that proteolysis at the Glu(441)-Ala(442) peptide bond in the V1 isoform is essential for interdigital web regression
por: Nandadasa, Sumeda, et al.
Publicado: (2021)

High molecular weight hyaluronan protects cartilage from degradation by inhibiting aggrecanase expression
por: Ohtsuki, Takashi, et al.
Publicado: (2018)

Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate
por: Nandadasa, Sumeda, et al.
Publicado: (2023)

Induction of CEMIP in Chondrocytes by Inflammatory Cytokines: Underlying Mechanisms and Potential Involvement in Osteoarthritis
por: Ohtsuki, Takashi, et al.
Publicado: (2020)

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis
por: Nandadasa, Sumeda, et al.
Publicado: (2019)

5-Year Survival in Gastric Adenocarcinoma with Epithelial and Stromal Versican Expression
por: Sanei, Mohammad Hossein, et al.
Publicado: (2019)

Regulation of Classical Cadherin Membrane Expression and F-Actin Assembly by Alpha-Catenins, during Xenopus Embryogenesis
por: Nandadasa, Sumeda, et al.
Publicado: (2012)

Plasma versican and plasma exosomal versican as potential diagnostic markers for non-small cell lung cancer
por: Chang, Wenjing, et al.
Publicado: (2023)

Inflammation Amplification by Versican: The First Mediator
por: Zhang, Zhenwei, et al.
Publicado: (2012)

Versican is crucial for the initiation of cardiovascular lumen development in medaka (Oryzias latipes)
por: Mittal, Nishant, et al.
Publicado: (2019)

Versican is differentially regulated in the adventitial and medial layers of human vein grafts
por: Kenagy, Richard D., et al.
Publicado: (2018)

Versican Expression during Synovial Joint Morphogenesis
por: Shepard, John B., et al.
Publicado: (2007)

Prognostic significance of Versican expression in gastric adenocarcinoma
por: Shen, X-H, et al.
Publicado: (2015)

Versican contributes to ligament formation of knee joints
por: Higuchi, Tomoko, et al.
Publicado: (2021)

Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican
por: Hong, Courtney C., et al.
Publicado: (2020)

Versican in inflammation and tissue remodeling: The impact on lung disorders
por: Andersson-Sjöland, Annika, et al.
Publicado: (2015)

Role of Versican and ADAMTS-1 in Polycystic Ovary Syndrome
por: Özler, Sibel, et al.
Publicado: (2017)

Identification of Versican as an Independent Prognostic Factor in Uveal Melanoma
por: Xu, Jia, et al.
Publicado: (2021)

ADAMTS4 and ADAMTS5 Knockout Mice Are Protected from Versican but Not Aggrecan or Brevican Proteolysis during Spinal Cord Injury
por: Demircan, Kadir, et al.
Publicado: (2014)

Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth
por: Nandadasa, Sumeda, et al.
Publicado: (2020)

Hormone-regulated expression and distribution of versican in mouse uterine tissues
por: Salgado, Renato M, et al.
Publicado: (2009)

Role of Versican, Hyaluronan and CD44 in Ovarian Cancer Metastasis
por: Ween, Miranda P., et al.
Publicado: (2011)

Versican regulates metastasis of epithelial ovarian carcinoma cells and spheroids
por: Desjardins, Mark, et al.
Publicado: (2014)

Association of Versican Turnover with All-Cause Mortality in Patients on Haemodialysis
por: Genovese, Federica, et al.
Publicado: (2014)

Mechanisms of Hypoxic Up-Regulation of Versican Gene Expression in Macrophages
por: Sotoodehnejadnematalahi, Fattah, et al.
Publicado: (2015)

Versican—A Critical Extracellular Matrix Regulator of Immunity and Inflammation
por: Wight, Thomas N., et al.
Publicado: (2020)

Targeting Versican as a Potential Immunotherapeutic Strategy in the Treatment of Cancer
por: Hirani, Priyanka, et al.
Publicado: (2021)

Gene Expression and Immunochemistry Analysis of ADAMTS-1 and Versican in Ameloblastoma
por: de Souza Neto, Osvaldo Rodrigues, et al.
Publicado: (2022)

Versican is expressed in the proliferating zone in the epidermis and in association with the elastic network of the dermis
Publicado: (1994)

Immunohistochemical and biochemical assay of versican in human sound predentine/dentine matrix
por: Ruggeri, A., et al.
Publicado: (2009)

Increased Renal Versican Expression Is Associated with Progression of Chronic Kidney Disease
por: Rudnicki, Michael, et al.
Publicado: (2012)

Estradiol induces transcriptional and posttranscriptional modifications in versican expression in the mouse uterus
por: Salgado, Renato M., et al.
Publicado: (2012)

Canine carcinomas in benign mixed tumours: versican expression and association with invasion
por: Damasceno, Karine A, et al.
Publicado: (2013)

A family with Wagner syndrome with uveitis and a new versican mutation
por: Rothschild, Pierre-Raphaël, et al.
Publicado: (2013)

Versican is a potential therapeutic target in docetaxel-resistant prostate cancer
por: Arichi, Naoko, et al.
Publicado: (2015)

Sharpin promotes hepatocellular carcinoma progression via transactivation of Versican expression
por: Tanaka, Y, et al.
Publicado: (2016)

Lumican and versican protein expression are associated with colorectal adenoma-to-carcinoma progression
por: de Wit, Meike, et al.
Publicado: (2017)

Additional Wide Resection of Infantile Dermatofibrosarcoma Protuberans after Unplanned Excision: A Case Report
por: Tanaka, Tomoharu, et al.
Publicado: (2023)

Interleukin-11 Promotes the Progress of Gastric Carcinoma via Abnormally Expressed Versican
por: Zhang, Zhenwei, et al.
Publicado: (2012)

Expression of Versican 3′-Untranslated Region Modulates Endogenous MicroRNA Functions
por: Lee, Daniel Y., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_s8oeb9rkmlvmsdr1tokhch8b7s