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Probenecid arrests the progression of pronounced clinical symptoms in a mouse model of multiple sclerosis

While it has been established that Probenecid (PBN) prevents the onset of experimental autoimmune encephalomyelitis (EAE) in mice, it is not clear whether it has any effect on already manifest EAE. The aim of this study was therefore to analyze the therapeutic effect of PBN in pronounced EAE. Mice w...

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Detalles Bibliográficos
Autores principales: Hainz, Nadine, Wolf, Sandra, Beck, Artjom, Wagenpfeil, Stefan, Tschernig, Thomas, Meier, Carola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722901/
https://www.ncbi.nlm.nih.gov/pubmed/29222419
http://dx.doi.org/10.1038/s41598-017-17517-5