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Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families
Protein disulfide isomerases (PDIs) support endoplasmic reticulum redox protein folding and cell-surface thiol-redox control of thrombosis and vascular remodeling. The family prototype PDIA1 regulates NADPH oxidase signaling and cytoskeleton organization, however the related underlying mechanisms ar...
Autores principales: | Moretti, Ana I. S., Pavanelli, Jessyca C., Nolasco, Patrícia, Leisegang, Matthias S., Tanaka, Leonardo Y., Fernandes, Carolina G., Wosniak, João, Kajihara, Daniela, Dias, Matheus H., Fernandes, Denise C., Jo, Hanjoong, Tran, Ngoc-Vinh, Ebersberger, Ingo, Brandes, Ralf P., Bonatto, Diego, Laurindo, Francisco R. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722932/ https://www.ncbi.nlm.nih.gov/pubmed/29222525 http://dx.doi.org/10.1038/s41598-017-16947-5 |
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