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Zinc deficiency as a codeterminant for airway epithelial barrier dysfunction in an ex vivo model of COPD
There is now convincing evidence that the airway epithelium drives the pathogenesis of COPD. A major aspect of this is the disease-related reduction in barrier function that is potentiated by dysregulation of tight junction (TJ) protein complexes. However, a significant number of studies using in vi...
Autores principales: | Roscioli, Eugene, Jersmann, Hubertus PA, Lester, Susan, Badiei, Arash, Fon, Andrew, Zalewski, Peter, Hodge, Sandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723110/ https://www.ncbi.nlm.nih.gov/pubmed/29255357 http://dx.doi.org/10.2147/COPD.S149589 |
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