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Stem-loop structure preference for site-specific RNA editing by APOBEC3A and APOBEC3G

APOBEC3A and APOBEC3G cytidine deaminases inhibit viruses and endogenous retrotransposons. We recently demonstrated the novel cellular C-to-U RNA editing function of APOBEC3A and APOBEC3G. Both enzymes deaminate single-stranded DNAs at multiple TC or CC nucleotide sequences, but edit only a select s...

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Detalles Bibliográficos
Autores principales: Sharma, Shraddha, Baysal, Bora E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723131/
https://www.ncbi.nlm.nih.gov/pubmed/29230368
http://dx.doi.org/10.7717/peerj.4136

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