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Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor
INTRODUCTION: Ectopic Cushing syndrome is a form of Cushing’s in which a tumor outside the pituitary gland produces adrenocorticotropic hormone (ACTH). Small cell carcinoma and carcinoid of the lung comprises half of its cases. The main purpose of this study is to present a case of ectopic Cushing s...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723367/ https://www.ncbi.nlm.nih.gov/pubmed/29202350 http://dx.doi.org/10.1016/j.ijscr.2017.11.034 |
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author | Aljassem, Ghanem Aljasem, Hazem |
author_facet | Aljassem, Ghanem Aljasem, Hazem |
author_sort | Aljassem, Ghanem |
collection | PubMed |
description | INTRODUCTION: Ectopic Cushing syndrome is a form of Cushing’s in which a tumor outside the pituitary gland produces adrenocorticotropic hormone (ACTH). Small cell carcinoma and carcinoid of the lung comprises half of its cases. The main purpose of this study is to present a case of ectopic Cushing syndrome caused by a hidden lung carcinoid and how to manage it. PRESENTATION OF CASE: Here we present a case of a 26 year old young male complains of increased weight and appetite, proximal muscle weakness, easy bruising and appearing of purple striae on his abdomen, with a final diagnosis of ACTH secreting lung carcinoid. DISCUSSION: The diagnosis was made by non-invasive radiological procedures (CT scan and MRI) and serological tests. The management consisted of medical treatment which was not useful, then bilateral adrenalectomy to limit the patient symptoms. The ectopic spot was finally detected and excised surgically through thoracotomy. After six months of follow up there was no recurrence, signs and symptoms of Cushing syndrome begin to disappear. CONCLUSION: Ectopic cushing syndrome is a complicated medical problem especially when it comes to identification of the ectopic spot. The surgical treatment could be curative when the spot is determined. |
format | Online Article Text |
id | pubmed-5723367 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-57233672017-12-11 Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor Aljassem, Ghanem Aljasem, Hazem Int J Surg Case Rep Article INTRODUCTION: Ectopic Cushing syndrome is a form of Cushing’s in which a tumor outside the pituitary gland produces adrenocorticotropic hormone (ACTH). Small cell carcinoma and carcinoid of the lung comprises half of its cases. The main purpose of this study is to present a case of ectopic Cushing syndrome caused by a hidden lung carcinoid and how to manage it. PRESENTATION OF CASE: Here we present a case of a 26 year old young male complains of increased weight and appetite, proximal muscle weakness, easy bruising and appearing of purple striae on his abdomen, with a final diagnosis of ACTH secreting lung carcinoid. DISCUSSION: The diagnosis was made by non-invasive radiological procedures (CT scan and MRI) and serological tests. The management consisted of medical treatment which was not useful, then bilateral adrenalectomy to limit the patient symptoms. The ectopic spot was finally detected and excised surgically through thoracotomy. After six months of follow up there was no recurrence, signs and symptoms of Cushing syndrome begin to disappear. CONCLUSION: Ectopic cushing syndrome is a complicated medical problem especially when it comes to identification of the ectopic spot. The surgical treatment could be curative when the spot is determined. Elsevier 2017-11-28 /pmc/articles/PMC5723367/ /pubmed/29202350 http://dx.doi.org/10.1016/j.ijscr.2017.11.034 Text en © 2017 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Aljassem, Ghanem Aljasem, Hazem Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor |
title | Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor |
title_full | Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor |
title_fullStr | Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor |
title_full_unstemmed | Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor |
title_short | Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor |
title_sort | case report: ectopic cushing’s syndrome in a young male with hidden lung carcinoid tumor |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723367/ https://www.ncbi.nlm.nih.gov/pubmed/29202350 http://dx.doi.org/10.1016/j.ijscr.2017.11.034 |
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