Cargando…

Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor

INTRODUCTION: Ectopic Cushing syndrome is a form of Cushing’s in which a tumor outside the pituitary gland produces adrenocorticotropic hormone (ACTH). Small cell carcinoma and carcinoid of the lung comprises half of its cases. The main purpose of this study is to present a case of ectopic Cushing s...

Descripción completa

Detalles Bibliográficos
Autores principales: Aljassem, Ghanem, Aljasem, Hazem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723367/
https://www.ncbi.nlm.nih.gov/pubmed/29202350
http://dx.doi.org/10.1016/j.ijscr.2017.11.034
_version_ 1783285198076510208
author Aljassem, Ghanem
Aljasem, Hazem
author_facet Aljassem, Ghanem
Aljasem, Hazem
author_sort Aljassem, Ghanem
collection PubMed
description INTRODUCTION: Ectopic Cushing syndrome is a form of Cushing’s in which a tumor outside the pituitary gland produces adrenocorticotropic hormone (ACTH). Small cell carcinoma and carcinoid of the lung comprises half of its cases. The main purpose of this study is to present a case of ectopic Cushing syndrome caused by a hidden lung carcinoid and how to manage it. PRESENTATION OF CASE: Here we present a case of a 26 year old young male complains of increased weight and appetite, proximal muscle weakness, easy bruising and appearing of purple striae on his abdomen, with a final diagnosis of ACTH secreting lung carcinoid. DISCUSSION: The diagnosis was made by non-invasive radiological procedures (CT scan and MRI) and serological tests. The management consisted of medical treatment which was not useful, then bilateral adrenalectomy to limit the patient symptoms. The ectopic spot was finally detected and excised surgically through thoracotomy. After six months of follow up there was no recurrence, signs and symptoms of Cushing syndrome begin to disappear. CONCLUSION: Ectopic cushing syndrome is a complicated medical problem especially when it comes to identification of the ectopic spot. The surgical treatment could be curative when the spot is determined.
format Online
Article
Text
id pubmed-5723367
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-57233672017-12-11 Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor Aljassem, Ghanem Aljasem, Hazem Int J Surg Case Rep Article INTRODUCTION: Ectopic Cushing syndrome is a form of Cushing’s in which a tumor outside the pituitary gland produces adrenocorticotropic hormone (ACTH). Small cell carcinoma and carcinoid of the lung comprises half of its cases. The main purpose of this study is to present a case of ectopic Cushing syndrome caused by a hidden lung carcinoid and how to manage it. PRESENTATION OF CASE: Here we present a case of a 26 year old young male complains of increased weight and appetite, proximal muscle weakness, easy bruising and appearing of purple striae on his abdomen, with a final diagnosis of ACTH secreting lung carcinoid. DISCUSSION: The diagnosis was made by non-invasive radiological procedures (CT scan and MRI) and serological tests. The management consisted of medical treatment which was not useful, then bilateral adrenalectomy to limit the patient symptoms. The ectopic spot was finally detected and excised surgically through thoracotomy. After six months of follow up there was no recurrence, signs and symptoms of Cushing syndrome begin to disappear. CONCLUSION: Ectopic cushing syndrome is a complicated medical problem especially when it comes to identification of the ectopic spot. The surgical treatment could be curative when the spot is determined. Elsevier 2017-11-28 /pmc/articles/PMC5723367/ /pubmed/29202350 http://dx.doi.org/10.1016/j.ijscr.2017.11.034 Text en © 2017 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Aljassem, Ghanem
Aljasem, Hazem
Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor
title Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor
title_full Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor
title_fullStr Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor
title_full_unstemmed Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor
title_short Case report: Ectopic Cushing’s syndrome in a young male with hidden lung carcinoid tumor
title_sort case report: ectopic cushing’s syndrome in a young male with hidden lung carcinoid tumor
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723367/
https://www.ncbi.nlm.nih.gov/pubmed/29202350
http://dx.doi.org/10.1016/j.ijscr.2017.11.034
work_keys_str_mv AT aljassemghanem casereportectopiccushingssyndromeinayoungmalewithhiddenlungcarcinoidtumor
AT aljasemhazem casereportectopiccushingssyndromeinayoungmalewithhiddenlungcarcinoidtumor