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T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes

Type 1 diabetes (T1D) results from destruction of pancreatic beta cells by T cells of the immune system. Despite improvements in insulin analogs and continuous blood glucose level monitoring, there is no cure for T1D, and some individuals develop life-threatening complications. Pancreas and islet tr...

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Detalles Bibliográficos
Autores principales:	Burrack, Adam L., Martinov, Tijana, Fife, Brian T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723426/ https://www.ncbi.nlm.nih.gov/pubmed/29259578 http://dx.doi.org/10.3389/fendo.2017.00343

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