Advantages of inflatable multichannel endorectal applicator in the neo‐adjuvant treatment of patients with locally advanced rectal cancer with HDR brachytherapy

High‐dose rate endorectal brachytherapy (HDR‐EBT) is mainly used as a palliative treatment modality. In this paper, we compare dosimetry distributions for a single‐channel catheter (Miami) applicator with distributions of the inflatable multichannel (Novi Sad) endorectal applicator. The comparisons...

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Detalles Bibliográficos
Autores principales: Devic, Slobodan, Vuong, Té, Moftah, Belal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2005
Materias:
Radiation Oncology Physics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723468/
https://www.ncbi.nlm.nih.gov/pubmed/15940211
http://dx.doi.org/10.1120/jacmp.v6i2.2029
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author Devic, Slobodan
Vuong, Té
Moftah, Belal
author_facet Devic, Slobodan
Vuong, Té
Moftah, Belal
author_sort Devic, Slobodan
collection PubMed
description High‐dose rate endorectal brachytherapy (HDR‐EBT) is mainly used as a palliative treatment modality. In this paper, we compare dosimetry distributions for a single‐channel catheter (Miami) applicator with distributions of the inflatable multichannel (Novi Sad) endorectal applicator. The comparisons were made with respect to dose coverage to the clinical tumor volume as well as to the bladder, rectal wall, prostate, and bone marrow. Our results suggest that a multichannel applicator provides better sparing of the bone marrow by 50%, clinically uninvolved parts of the rectal wall by 70%, and bladder and prostate (in the case of male patients) by 100% in terms of ratio of median doses to critical organ volume for single‐ and multichannel endorectal applicators. Our results justify the advantage of using a multichannel endorectal brachytherapy applicator as a neo‐adjuvant treatment of patients with locally advanced rectal cancer. PACS numbers: 87.53.Jw, 87.53.Tf
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spelling pubmed-57234682018-04-02 Advantages of inflatable multichannel endorectal applicator in the neo‐adjuvant treatment of patients with locally advanced rectal cancer with HDR brachytherapy Devic, Slobodan Vuong, Té Moftah, Belal J Appl Clin Med Phys Radiation Oncology Physics High‐dose rate endorectal brachytherapy (HDR‐EBT) is mainly used as a palliative treatment modality. In this paper, we compare dosimetry distributions for a single‐channel catheter (Miami) applicator with distributions of the inflatable multichannel (Novi Sad) endorectal applicator. The comparisons were made with respect to dose coverage to the clinical tumor volume as well as to the bladder, rectal wall, prostate, and bone marrow. Our results suggest that a multichannel applicator provides better sparing of the bone marrow by 50%, clinically uninvolved parts of the rectal wall by 70%, and bladder and prostate (in the case of male patients) by 100% in terms of ratio of median doses to critical organ volume for single‐ and multichannel endorectal applicators. Our results justify the advantage of using a multichannel endorectal brachytherapy applicator as a neo‐adjuvant treatment of patients with locally advanced rectal cancer. PACS numbers: 87.53.Jw, 87.53.Tf John Wiley and Sons Inc. 2005-05-21 /pmc/articles/PMC5723468/ /pubmed/15940211 http://dx.doi.org/10.1120/jacmp.v6i2.2029 Text en © 2005 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Devic, Slobodan
Vuong, Té
Moftah, Belal
Advantages of inflatable multichannel endorectal applicator in the neo‐adjuvant treatment of patients with locally advanced rectal cancer with HDR brachytherapy
title Advantages of inflatable multichannel endorectal applicator in the neo‐adjuvant treatment of patients with locally advanced rectal cancer with HDR brachytherapy
title_full Advantages of inflatable multichannel endorectal applicator in the neo‐adjuvant treatment of patients with locally advanced rectal cancer with HDR brachytherapy
title_fullStr Advantages of inflatable multichannel endorectal applicator in the neo‐adjuvant treatment of patients with locally advanced rectal cancer with HDR brachytherapy
title_full_unstemmed Advantages of inflatable multichannel endorectal applicator in the neo‐adjuvant treatment of patients with locally advanced rectal cancer with HDR brachytherapy
title_short Advantages of inflatable multichannel endorectal applicator in the neo‐adjuvant treatment of patients with locally advanced rectal cancer with HDR brachytherapy
title_sort advantages of inflatable multichannel endorectal applicator in the neo‐adjuvant treatment of patients with locally advanced rectal cancer with hdr brachytherapy
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723468/
https://www.ncbi.nlm.nih.gov/pubmed/15940211
http://dx.doi.org/10.1120/jacmp.v6i2.2029
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AT moftahbelal advantagesofinflatablemultichannelendorectalapplicatorintheneoadjuvanttreatmentofpatientswithlocallyadvancedrectalcancerwithhdrbrachytherapy

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