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Planning quality and delivery efficiency of sMLC delivered IMRT treatment of oropharyngeal cancers evaluated by RTOG H‐0022 dosimetric criteria

The time required to deliver intensity‐modulated radiation therapy (IMRT) treatments can be significantly longer than conventional treatments, especially for the segmented multileaf collimator (sMLC) delivery system with a large record and verification (R&V) overhead. In this work, we evaluate t...

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Detalles Bibliográficos
Autores principales: Zhu, X. Ronald, Schultz, Christopher J., Gillin, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723523/
https://www.ncbi.nlm.nih.gov/pubmed/15738923
http://dx.doi.org/10.1120/jacmp.v5i4.2014
Descripción
Sumario:The time required to deliver intensity‐modulated radiation therapy (IMRT) treatments can be significantly longer than conventional treatments, especially for the segmented multileaf collimator (sMLC) delivery system with a large record and verification (R&V) overhead. In this work, we evaluate the impact of the number of intensity‐modulated beams (IMBs) and the number of intensity levels (ILs) on the quality and delivery efficiency of IMRT plans, generated by the Corvus planning system for sMLC delivery on a Siemens LINAC with the Lantis R&V system. Detailed studies were performed for three image data sets of previously treated oropharyngeal patients. Treatment plans for patient 1 were developed using 5, 7, 9, or 15 evenly spaced axial IMBs as well as one with 7 axial IMBs whose directions were user‐selected, each using ILs of 3, 5, 10, or 20. For patients 2 and 3, plans with 15 IMBs and 20 ILs were not attempted. A total of 42 plans were developed using three oropharyngeal cancer CT image data sets. Plan quality was evaluated by assessing compliance with the Radiation Therapy Oncology Group (RTOG) H‐0022 protocol criteria and the physician's clinical judgment. Plan efficiency was accessed by the number of segments of each plan. We found that for our treatment‐planning and delivery system, an IMRT plan that uses a moderate number of IMBs and ILs, such as 7 or 9 IMBs with 3 or 5 ILs, would appear to be the optimal approach when both quality of the plan and delivery efficiency are considered. Based on this study, we have routinely used 9 IMBs with 3 ILs or 7 IMBs with 5 ILs for head and neck patients. A retrospective comparison indicates that delivery efficiency is improved on the order of 30% compared to plans generated with 9 IMBs with 5 ILs. PACS number: 87.53.Tf