Disseminated Tuberculosis and Chronic Mucocutaneous Candidiasis in a Patient with a Gain-of-Function Mutation in Signal Transduction and Activator of Transcription 1

In humans, recessive loss-of-function mutations in STAT1 are associated with mycobacterial and viral infections, whereas gain-of-function (GOF) mutations in STAT1 are associated with a type of primary immunodeficiency related mainly, but not exclusively, to chronic mucocutaneous candidiasis (CMC). W...

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Detalles Bibliográficos
Autores principales: Pedraza-Sánchez, Sigifredo, Lezana-Fernández, Jose Luis, Gonzalez, Yolanda, Martínez-Robles, Luis, Ventura-Ayala, María Laura, Sadowinski-Pine, Stanislaw, Nava-Frías, Margarita, Moreno-Espinosa, Sarbelio, Casanova, Jean-Laurent, Puel, Anne, Boisson-Dupuis, Stephanie, Torres, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723642/
https://www.ncbi.nlm.nih.gov/pubmed/29270166
http://dx.doi.org/10.3389/fimmu.2017.01651

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