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Residual γH2AX foci induced by low dose x-ray radiation in bone marrow mesenchymal stem cells do not cause accelerated senescence in the progeny of irradiated cells

Mechanisms underlying the effects of low-dose ionizing radiation (IR) exposure (10-100 mGy) remain unknown. Here we present a comparative study of early (less than 24h) and delayed (up to 11 post-irradiation passages) radiation effects caused by low (80 mGy) vs intermediate (1000 mGy) dose X-ray exp...

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Detalles Bibliográficos
Autores principales: Pustovalova, Margarita, Astrelina, Тatiana A., Grekhova, Anna, Vorobyeva, Natalia, Tsvetkova, Anastasia, Blokhina, Taisia, Nikitina, Victoria, Suchkova, Yulia, Usupzhanova, Daria, Brunchukov, Vitalyi, Kobzeva, Irina, Karaseva, Тatiana, Ozerov, Ivan V., Samoylov, Aleksandr, Bushmanov, Andrey, Leonov, Sergey, Izumchenko, Evgeny, Zhavoronkov, Alex, Klokov, Dmitry, Osipov, Andreyan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723693/
https://www.ncbi.nlm.nih.gov/pubmed/29165316
http://dx.doi.org/10.18632/aging.101327