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Cenerimod, a novel selective S1P(1) receptor modulator with unique signaling properties

Sphingosine‐1‐phosphate receptor 1 (S1P(1)) modulators sequester circulating lymphocytes within lymph nodes, thereby preventing potentially pathogenic autoimmune cells from exiting into the blood stream and reaching inflamed tissues. S1P(1) receptor modulation may thus offer potential to treat vario...

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Detalles Bibliográficos
Autores principales: Piali, Luca, Birker‐Robaczewska, Magdalena, Lescop, Cyrille, Froidevaux, Sylvie, Schmitz, Nicole, Morrison, Keith, Kohl, Christopher, Rey, Markus, Studer, Rolf, Vezzali, Enrico, Hess, Patrick, Clozel, Martine, Steiner, Beat, Bolli, Martin H., Nayler, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723703/
https://www.ncbi.nlm.nih.gov/pubmed/29226621
http://dx.doi.org/10.1002/prp2.370