Cargando…

The Evaluation of Toxicity Induced by Psoraleae Fructus in Rats Using Untargeted Metabonomic Method Based on UPLC-Q-TOF/MS

Psoraleae Fructus is the dry and mature fruit of leguminous plant Psoralea corylifolia L., with the activity of warming kidney and enhancing yang, warming spleen, and other effects. However, large doses can cause liver and kidney toxicity. Therefore, it is necessary to evaluate the toxicity of Psora...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Yanyan, Zhao, Yiwei, Xie, Jiabin, Sheng, Xue, Li, Yubo, Zhang, Yanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723950/ https://www.ncbi.nlm.nih.gov/pubmed/29279717 http://dx.doi.org/10.1155/2017/6207183

Ejemplares similares

UPLC-MS/MS-Based Rat Serum Metabolomics Reveals the Detoxification Mechanism of Psoraleae Fructus during Salt Processing
por: Wang, Dan, et al.
Publicado: (2021)

Plasma metabolic profiling analysis of Cortex Periplocae-induced cardiotoxicity based on UPLC/Q-TOF-MS
por: Li, Yubo, et al.
Publicado: (2018)

UPLC/Q-TOF MS-Based Urine Metabonomics Study to Identify Diffuse Axonal Injury Biomarkers in Rat
por: Zhang, Peng, et al.
Publicado: (2022)

Potential serum biomarkers and metabonomic profiling of serum in ischemic stroke patients using UPLC/Q-TOF MS/MS
por: Sun, Hongxue, et al.
Publicado: (2017)

High-Throughput Untargeted Serum Metabolomics Analysis of Hyperuricemia Patients by UPLC-Q-TOF/MS
por: Qin, Nankun, et al.
Publicado: (2021)

UPLC-Q-TOF/MS-based metabonomic studies on the intervention effects of aspirin eugenol ester in atherosclerosis hamsters
por: Ma, Ning, et al.
Publicado: (2017)

Protective effect and mechanism of styrax on ischemic stroke rats: metabonomic insights by UPLC-Q/TOF-MS analysis
por: Mu, Fei, et al.
Publicado: (2023)

Untargeted metabonomic analysis of a cerebral stroke model in rats: a study based on UPLC–MS/MS
por: Huang, Dunbing, et al.
Publicado: (2023)

General survey of Fructus Psoraleae from the different origins and chemical identification of the roasted from raw Fructus Psoraleae
por: Yang, Junjun, et al.
Publicado: (2017)

Rapid Screening of Chemical Constituents in Rhizoma Anemarrhenae by UPLC-Q-TOF/MS Combined with Data Postprocessing Techniques
por: Shan, Lanlan, et al.
Publicado: (2017)

Exploration of the anti-hyperuricemia effect of TongFengTangSan (TFTS) by UPLC-Q-TOF/MS-based non-targeted metabonomics
por: Huang, Zhichao, et al.
Publicado: (2023)

Preliminary observational study of metabonomics in patients with early and late-onset type 2 diabetes mellitus based on UPLC-Q-TOF/MS
por: Hao, Zhaohu, et al.
Publicado: (2023)

Based on UPLC-Q-TOF-MS/MS, Systematic Network Pharmacology, and Molecular Docking to Explore the Potential Mechanism of Fructus Aurantii for Major Depression Disorder
por: Xie, Yating, et al.
Publicado: (2021)

Rapid Classification and Identification of Chemical Components of Schisandra Chinensis by UPLC-Q-TOF/MS Combined with Data Post-Processing
por: Yang, Shenshen, et al.
Publicado: (2017)

Analysis of E. rutaecarpa Alkaloids Constituents In Vitro and In Vivo by UPLC-Q-TOF-MS Combined with Diagnostic Fragment
por: Yang, Shenshen, et al.
Publicado: (2016)

Quality Evaluation of Tricholoma matsutake Based on the Nucleic Acid Compounds by UPLC-TOF/MS and UPLC-QqQ/MS
por: Xue, Ying, et al.
Publicado: (2018)

UPLC-Q-TOF/MS-Based Serum and Urine Metabonomics Study on the Ameliorative Effects of Palmatine on Helicobacter pylori–Induced Chronic Atrophic Gastritis
por: Chen, Xing, et al.
Publicado: (2020)

UPLC-Q-TOF/MS-based metabonomics reveals mechanisms for Holothuria leucospilota polysaccharides (HLP)-regulated serum metabolic changes in diabetic rats
por: Zhang, Xin, et al.
Publicado: (2023)

Identification of Sanguinarine Metabolites in Rats Using UPLC-Q-TOF-MS/MS
por: Liu, Mengting, et al.
Publicado: (2023)

Simultaneous Analysis of Iridoid Glycosides and Anthraquinones in Morinda officinalis Using UPLC-QqQ-MS/MS and UPLC-Q/TOF-MS(E)
por: Zhao, Xiangsheng, et al.
Publicado: (2018)

Anti-melanoma activity of Forsythiae Fructus aqueous extract in mice involves regulation of glycerophospholipid metabolisms by UPLC/Q-TOF MS-based metabolomics study
por: Bao, Jiaolin, et al.
Publicado: (2016)

Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS
por: Li, Limin, et al.
Publicado: (2020)

Characterization of Ginsenosides from the Root of Panax ginseng by Integrating Untargeted Metabolites Using UPLC-Triple TOF-MS
por: Sun, Yizheng, et al.
Publicado: (2023)

UPLC-Q-TOF-MS Study of the Mechanism of THSWD for Breast Cancer Treatment
por: Duan, Xianchun, et al.
Publicado: (2020)

Identification of absorbed constituents and evaluation of the pharmacokinetics of main compounds after oral administration of yindanxinnaotong by UPLC-Q-TOF-MS and UPLC-QqQ-MS
por: Gong, Leilei, et al.
Publicado: (2018)

Identification and Comparison of Constituents of Aurantii Fructus and Aurantii Fructus Immaturus by UFLC-DAD-Triple TOF-MS/MS
por: Bai, Yang, et al.
Publicado: (2018)

Integration of (1)H NMR and UPLC-Q-TOF/MS for a Comprehensive Urinary Metabonomics Study on a Rat Model of Depression Induced by Chronic Unpredictable Mild Stress
por: Jia, Hong-mei, et al.
Publicado: (2013)

Untargeted Metabolomics Analysis Using UHPLC-Q-TOF/MS Reveals Metabolic Changes Associated with Hypertension in Children
por: Zhang, Kexin, et al.
Publicado: (2023)

UPLC-Q-TOF/MS-based metabolomic analysis reveals the effects of asomate on the citrus fruit
por: He, Guangyun, et al.
Publicado: (2023)

Identification of Components in Citri Sarcodactylis Fructus from Different Origins via UPLC-Q-Exactive Orbitrap/MS
por: Wang, Kanghui, et al.
Publicado: (2021)

Metabonomics study on the hepatoprotective effect mechanism of polysaccharides from different processed products of Angelica sinensis on layer chickens based on UPLC–Q/TOF–MS/MS, multivariate statistical analysis and conjoint analysis
por: Wu, Fan‐lin, et al.
Publicado: (2022)

UPLC/Q-TOF-MS based plasma metabolomics and clinical characteristics of polycystic ovarian syndrome
por: Fan, Xuemei, et al.
Publicado: (2019)

Serum biomarkers of the calcium-deficient rats identified by metabolomics based on UPLC/Q-TOF MS/MS
por: Meng, Fanyu, et al.
Publicado: (2020)

Chemical Profiling of Xueshuan Xinmaining Tablet by HPLC and UPLC-ESI-Q-TOF/MS
por: Han, Ya-Xin, et al.
Publicado: (2018)

Assessing the quality of Smilacis Glabrae Rhizoma (Tufuling) by colormetrics and UPLC-Q-TOF-MS
por: He, Xicheng, et al.
Publicado: (2016)

Evaluation of Microbial Transformation of 10-deoxoartemisinin by UPLC-ESI-Q-TOF-MS(E)
por: Bai, Yue, et al.
Publicado: (2019)

Comprehensive metabolomics study on the pathogenesis of anaplastic astrocytoma via UPLC-Q/TOF-MS
por: Du, Chao, et al.
Publicado: (2022)

Quality Assessment of Psoralea fructus by HPLC Fingerprint Coupled with Multi-components Analysis
por: Yin, F. Z., et al.
Publicado: (2015)

The Extract of Fructus Psoraleae Promotes Viability and Cartilaginous Formation of Rat Chondrocytes In Vitro
por: Pan, Xin, et al.
Publicado: (2016)

Rapid Identification of Characteristic Chemical Constituents of Panax ginseng, Panax quinquefolius, and Panax japonicus Using UPLC-Q-TOF/MS
por: Jinbiao, Liu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2mgoal6g968vtovt9vggs0ok9b