Cargando…

Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease

INTRODUCTION: Basal cell carcinoma (BCC) is considered the most common malignancy in Caucasians. It constituted about 80% of all nonmelanoma skin tumors and, despite its high prevalence, is an extremely rare occurrence of metastases, with incidence rates varying from 0.0028% to 0.55%. CASE REPORT: A...

Descripción completa

Detalles Bibliográficos
Autores principales: Piva de Freitas, Paola, Senna, César Galusni, Tabai, Mayara, Chone, Carlos Takahiro, Altemani, Albina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723960/
https://www.ncbi.nlm.nih.gov/pubmed/29279714
http://dx.doi.org/10.1155/2017/8929745
_version_ 1783285274784038912
author Piva de Freitas, Paola
Senna, César Galusni
Tabai, Mayara
Chone, Carlos Takahiro
Altemani, Albina
author_facet Piva de Freitas, Paola
Senna, César Galusni
Tabai, Mayara
Chone, Carlos Takahiro
Altemani, Albina
author_sort Piva de Freitas, Paola
collection PubMed
description INTRODUCTION: Basal cell carcinoma (BCC) is considered the most common malignancy in Caucasians. It constituted about 80% of all nonmelanoma skin tumors and, despite its high prevalence, is an extremely rare occurrence of metastases, with incidence rates varying from 0.0028% to 0.55%. CASE REPORT: A 58-year-old male patient with BCC on the left nasolabial sulcus for 17 years, reporting 3 previous excisions, evolved with local recurrence. A new procedure was performed, and anatomopathological study confirmed sclerosing BCC. Seven months later, he presented with a mass in the left submandibular region. Combined positron-emission tomography and computed tomography (PET-CT) showed cervical hypercaptation in the left cervical level I and vertebral body of L5. Excision of the cervical lesion was performed with diagnosis of sclerosing BCC compromising the submandibular gland. Biopsy of the lumbar lesion was found to be compatible with bone metastasis. CONCLUSION: BCC represents a very common entity, and the presence of metastasis, although infrequent, must be proposed because of the greater morbidity and mortality of this complication. This case shows the importance of early diagnosis and intervention in BCC as a way to avoid unfavorable outcomes.
format Online
Article
Text
id pubmed-5723960
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-57239602017-12-26 Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease Piva de Freitas, Paola Senna, César Galusni Tabai, Mayara Chone, Carlos Takahiro Altemani, Albina Case Rep Med Case Report INTRODUCTION: Basal cell carcinoma (BCC) is considered the most common malignancy in Caucasians. It constituted about 80% of all nonmelanoma skin tumors and, despite its high prevalence, is an extremely rare occurrence of metastases, with incidence rates varying from 0.0028% to 0.55%. CASE REPORT: A 58-year-old male patient with BCC on the left nasolabial sulcus for 17 years, reporting 3 previous excisions, evolved with local recurrence. A new procedure was performed, and anatomopathological study confirmed sclerosing BCC. Seven months later, he presented with a mass in the left submandibular region. Combined positron-emission tomography and computed tomography (PET-CT) showed cervical hypercaptation in the left cervical level I and vertebral body of L5. Excision of the cervical lesion was performed with diagnosis of sclerosing BCC compromising the submandibular gland. Biopsy of the lumbar lesion was found to be compatible with bone metastasis. CONCLUSION: BCC represents a very common entity, and the presence of metastasis, although infrequent, must be proposed because of the greater morbidity and mortality of this complication. This case shows the importance of early diagnosis and intervention in BCC as a way to avoid unfavorable outcomes. Hindawi 2017 2017-11-27 /pmc/articles/PMC5723960/ /pubmed/29279714 http://dx.doi.org/10.1155/2017/8929745 Text en Copyright © 2017 Paola Piva de Freitas et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Piva de Freitas, Paola
Senna, César Galusni
Tabai, Mayara
Chone, Carlos Takahiro
Altemani, Albina
Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title_full Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title_fullStr Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title_full_unstemmed Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title_short Metastatic Basal Cell Carcinoma: A Rare Manifestation of a Common Disease
title_sort metastatic basal cell carcinoma: a rare manifestation of a common disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723960/
https://www.ncbi.nlm.nih.gov/pubmed/29279714
http://dx.doi.org/10.1155/2017/8929745
work_keys_str_mv AT pivadefreitaspaola metastaticbasalcellcarcinomaararemanifestationofacommondisease
AT sennacesargalusni metastaticbasalcellcarcinomaararemanifestationofacommondisease
AT tabaimayara metastaticbasalcellcarcinomaararemanifestationofacommondisease
AT chonecarlostakahiro metastaticbasalcellcarcinomaararemanifestationofacommondisease
AT altemanialbina metastaticbasalcellcarcinomaararemanifestationofacommondisease