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Direct evidence for conformational dynamics in major histocompatibility complex class I molecules

Major histocompatibility complex class I molecules (MHC I) help protect jawed vertebrates by binding and presenting immunogenic peptides to cytotoxic T lymphocytes. Peptides are selected from a large diversity present in the endoplasmic reticulum. However, only a limited number of peptides complemen...

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Detalles Bibliográficos
Autores principales: van Hateren, Andy, Anderson, Malcolm, Bailey, Alistair, Werner, Jörn M., Skipp, Paul, Elliott, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724011/
https://www.ncbi.nlm.nih.gov/pubmed/29021251
http://dx.doi.org/10.1074/jbc.M117.809624