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Optimization of Experimental Parameters in Data-Independent Mass Spectrometry Significantly Increases Depth and Reproducibility of Results

Comprehensive, reproducible and precise analysis of large sample cohorts is one of the key objectives of quantitative proteomics. Here, we present an implementation of data-independent acquisition using its parallel acquisition nature that surpasses the limitation of serial MS2 acquisition of data-d...

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Detalles Bibliográficos
Autores principales:	Bruderer, Roland, Bernhardt, Oliver M., Gandhi, Tejas, Xuan, Yue, Sondermann, Julia, Schmidt, Manuela, Gomez-Varela, David, Reiter, Lukas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2017
Materias:	Technological Innovation and Resources
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724188/ https://www.ncbi.nlm.nih.gov/pubmed/29070702 http://dx.doi.org/10.1074/mcp.RA117.000314

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