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Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia

OBJECTIVES: We examined determinants of achieving blood pressure control in patients with hypertension and of treatment intensification in patients with uncontrolled blood pressure (BP). DESIGN: A retrospective cohort study in six public hospitals, Ethiopia. PARTICIPANTS: Adult ambulatory patients w...

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Autores principales: Berhe, Derbew Fikadu, Taxis, Katja, Haaijer-Ruskamp, Flora M, Mulugeta, Afework, Mengistu, Yewondwossen Tadesse, Mol, Peter G M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724212/
https://www.ncbi.nlm.nih.gov/pubmed/28775184
http://dx.doi.org/10.1136/bmjopen-2016-015743
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author Berhe, Derbew Fikadu
Taxis, Katja
Haaijer-Ruskamp, Flora M
Mulugeta, Afework
Mengistu, Yewondwossen Tadesse
Mol, Peter G M
author_facet Berhe, Derbew Fikadu
Taxis, Katja
Haaijer-Ruskamp, Flora M
Mulugeta, Afework
Mengistu, Yewondwossen Tadesse
Mol, Peter G M
author_sort Berhe, Derbew Fikadu
collection PubMed
description OBJECTIVES: We examined determinants of achieving blood pressure control in patients with hypertension and of treatment intensification in patients with uncontrolled blood pressure (BP). DESIGN: A retrospective cohort study in six public hospitals, Ethiopia. PARTICIPANTS: Adult ambulatory patients with hypertension and with at least one previously prescribed antihypertensive medication in the study hospital. OUTCOME: Controlled BP (<140/90 mm Hg) and treatment intensification of patients with uncontrolled BP. RESULTS: The study population comprised 897 patients. Their mean age was 57 (SD 14) years, 63% were females, and 35% had one or more cardiometabolic comorbidities mainly diabetes mellitus. BP was controlled in 37% of patients. Treatment was intensified for 23% patients with uncontrolled BP. In multivariable (logistic regression) analysis, determinants positively associated with controlled BP were treatment at general hospitals (OR 1.89, 95% CI 1.26 to 2.83) compared with specialised hospitals and longer treatment duration (OR 1.04, 95% CI 1.01 to 1.06). Negatively associated determinants were previously uncontrolled BP (OR 0.30, 95% CI 0.21 to 0.43), treatment regimens with diuretics (OR 0.68, 95% CI 0.50 to 0.94) and age (OR 0.99, 95% CI 0.98 to 1.00). The only significant—positive—determinant for treatment intensification was duration of therapy (OR 1.05, 95% CI 1.02 to 1.09). CONCLUSIONS: The level of controlled BP and treatment intensification practice in this study was low. The findings suggest the need for in-depth understanding and interventions of the identified determinants such as uncontrolled BP on consecutive visits, older age and type of hospital.
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spelling pubmed-57242122017-12-19 Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia Berhe, Derbew Fikadu Taxis, Katja Haaijer-Ruskamp, Flora M Mulugeta, Afework Mengistu, Yewondwossen Tadesse Mol, Peter G M BMJ Open Cardiovascular Medicine OBJECTIVES: We examined determinants of achieving blood pressure control in patients with hypertension and of treatment intensification in patients with uncontrolled blood pressure (BP). DESIGN: A retrospective cohort study in six public hospitals, Ethiopia. PARTICIPANTS: Adult ambulatory patients with hypertension and with at least one previously prescribed antihypertensive medication in the study hospital. OUTCOME: Controlled BP (<140/90 mm Hg) and treatment intensification of patients with uncontrolled BP. RESULTS: The study population comprised 897 patients. Their mean age was 57 (SD 14) years, 63% were females, and 35% had one or more cardiometabolic comorbidities mainly diabetes mellitus. BP was controlled in 37% of patients. Treatment was intensified for 23% patients with uncontrolled BP. In multivariable (logistic regression) analysis, determinants positively associated with controlled BP were treatment at general hospitals (OR 1.89, 95% CI 1.26 to 2.83) compared with specialised hospitals and longer treatment duration (OR 1.04, 95% CI 1.01 to 1.06). Negatively associated determinants were previously uncontrolled BP (OR 0.30, 95% CI 0.21 to 0.43), treatment regimens with diuretics (OR 0.68, 95% CI 0.50 to 0.94) and age (OR 0.99, 95% CI 0.98 to 1.00). The only significant—positive—determinant for treatment intensification was duration of therapy (OR 1.05, 95% CI 1.02 to 1.09). CONCLUSIONS: The level of controlled BP and treatment intensification practice in this study was low. The findings suggest the need for in-depth understanding and interventions of the identified determinants such as uncontrolled BP on consecutive visits, older age and type of hospital. BMJ Publishing Group 2017-08-03 /pmc/articles/PMC5724212/ /pubmed/28775184 http://dx.doi.org/10.1136/bmjopen-2016-015743 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Cardiovascular Medicine
Berhe, Derbew Fikadu
Taxis, Katja
Haaijer-Ruskamp, Flora M
Mulugeta, Afework
Mengistu, Yewondwossen Tadesse
Mol, Peter G M
Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia
title Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia
title_full Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia
title_fullStr Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia
title_full_unstemmed Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia
title_short Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia
title_sort hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in ethiopia
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724212/
https://www.ncbi.nlm.nih.gov/pubmed/28775184
http://dx.doi.org/10.1136/bmjopen-2016-015743
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