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Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer

Proinflammatory signaling pathways are commonly up-regulated in breast cancer. In estrogen receptor-negative (ER(−)) and triple-negative breast cancer (TNBC), nitric oxide synthase-2 (NOS2) and cyclooxygenase-2 (COX2) have been described as independent predictors of disease outcome. We further explo...

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Detalles Bibliográficos
Autores principales:	Basudhar, Debashree, Glynn, Sharon A., Greer, Madison, Somasundaram, Veena, No, Jae Hong, Scheiblin, David A., Garrido, Pablo, Heinz, William F., Ryan, Aideen E., Weiss, Jonathan M., Cheng, Robert Y. S., Ridnour, Lisa A., Lockett, Stephen J., McVicar, Daniel W., Ambs, Stefan, Wink, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2017
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724261/ https://www.ncbi.nlm.nih.gov/pubmed/29087320 http://dx.doi.org/10.1073/pnas.1709119114

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