Cargando…
The combination astemizole–gefitinib as a potential therapy for human lung cancer
Lung cancer is a major cause of cancer mortality. Thus, novel therapies are urgently needed. Repositioning of old drugs is gaining great interest in cancer treatment. Astemizole is an antihistamine proposed to be repositioned for cancer therapy. This drug targets several molecules involved in cancer...
Autores principales: | Chávez-López, María de Guadalupe, Zúñiga-García, Violeta, Hernández-Gallegos, Elisabeth, Vera, Eunice, Chasiquiza-Anchatuña, Carmen Alexandra, Viteri-Yánez, Marco, Sanchez-Ramos, Janet, Garrido, Efraín, Camacho, Javier |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724417/ https://www.ncbi.nlm.nih.gov/pubmed/29263676 http://dx.doi.org/10.2147/OTT.S144506 |
Ejemplares similares
-
Eag1 Gene and Protein Expression in Human Retinoblastoma Tumors and Its Regulation by pRb in HeLa Cells
por: Chávez-López, María de Guadalupe, et al.
Publicado: (2020) -
The effects of topical (gel) astemizole and terfenadine on wound healing
por: Srikanth, D., et al.
Publicado: (2008) -
Mechanism of Block of hEag1 K(+) Channels by Imipramine and Astemizole
por: García-Ferreiro, Rafael E., et al.
Publicado: (2004) -
Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking
por: Lyu, Junfang, et al.
Publicado: (2018) -
Astemizole as a drug to inhibit the effect of SARS-COV-2 in vitro
por: Wang, Xiangjun, et al.
Publicado: (2021)